Two-way traffic: centrosomes and the cell cycle - PubMed (original) (raw)
Review
doi: 10.1038/nrm1712.
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- PMID: 16231423
- DOI: 10.1038/nrm1712
Review
Two-way traffic: centrosomes and the cell cycle
Greenfield Sluder. Nat Rev Mol Cell Biol. 2005 Sep.
Abstract
The well recognized activities of the mammalian centrosome--microtubule nucleation, duplication, and organization of the primary cilium--are under the control of the cell cycle. However, the centrosome is more than just a follower of the cell cycle; it can also be essential for the cell to transit G1 and enter S phase. How the centrosome influences G1 progression is a mystery.
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