The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids - PubMed (original) (raw)
. 2005 Nov 21:(43):5438-40.
doi: 10.1039/b510707e. Epub 2005 Oct 4.
Affiliations
- PMID: 16261239
- DOI: 10.1039/b510707e
The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids
Biswadip Banerji et al. Chem Commun (Camb). 2005.
Abstract
Cyclic beta-oxocarboxylic acids inhibit factor inhibiting hypoxia-inducible factor via ligation to the active site iron.
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