Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene - PubMed (original) (raw)

Clinical characteristics and genotype-phenotype correlation analysis of familial Alzheimer's disease patients with pathogenic/likely pathogenic amyloid protein precursor mutations.

Liu Y, Xiao X, Liu H, Liao X, Zhou Y, Weng L, Zhou L, Liu X, Bi XY, Xu T, Zhu Y, Yang Q, Zhang S, Hao X, Zhang W, Wang J, Jiao B, Shen L. Liu Y, et al. Front Aging Neurosci. 2022 Oct 14;14:1013295. doi: 10.3389/fnagi.2022.1013295. eCollection 2022. Front Aging Neurosci. 2022. PMID: 36313020 Free PMC article.

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.

Morris JC, Weiner M, Xiong C, Beckett L, Coble D, Saito N, Aisen PS, Allegri R, Benzinger TLS, Berman SB, Cairns NJ, Carrillo MC, Chui HC, Chhatwal JP, Cruchaga C, Fagan AM, Farlow M, Fox NC, Ghetti B, Goate AM, Gordon BA, Graff-Radford N, Day GS, Hassenstab J, Ikeuchi T, Jack CR, Jagust WJ, Jucker M, Levin J, Massoumzadeh P, Masters CL, Martins R, McDade E, Mori H, Noble JM, Petersen RC, Ringman JM, Salloway S, Saykin AJ, Schofield PR, Shaw LM, Toga AW, Trojanowski JQ, Vöglein J, Weninger S, Bateman RJ, Buckles VD. Morris JC, et al. Brain. 2022 Oct 21;145(10):3594-3607. doi: 10.1093/brain/awac181. Brain. 2022. PMID: 35580594 Free PMC article.