Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells - PubMed (original) (raw)

Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells

Jasodhara Ray et al. Mol Cell Neurosci. 2006 Mar.

Abstract

Adult neurogenesis from neural stem/progenitor cells occurs in discrete regions of the central nervous system of all mammals, but the mechanisms regulating endogenous neurogenesis are poorly understood. Advances in understanding the neurogenesis depend on knowing their intrinsic properties and responses to environmental signals that control their behavior. Before these issues can be addressed, it is necessary to know whether there are significant species-specific differences in the properties of the stem/progenitor cells derived from CNS of two commonly studied model systems, mouse and rat. We found major differences between rat and mouse stem/progenitor cell proliferation in response to various substrates, mitogenic growth factors and heparin and to the influence of differentiation factors on generation of neurons and glia. Thus, extrapolation of cell properties from one species to another based on studies of these cells should be made with caution.

PubMed Disclaimer

Similar articles

• Mitogen and substrate differentially affect the lineage restriction of adult rat subventricular zone neural precursor cell populations.
  Whittemore SR, Morassutti DJ, Walters WM, Liu RH, Magnuson DS. Whittemore SR, et al. Exp Cell Res. 1999 Oct 10;252(1):75-95. doi: 10.1006/excr.1999.4621. Exp Cell Res. 1999. PMID: 10502401
• Region-specific growth properties and trophic requirements of brain- and spinal cord-derived rat embryonic neural precursor cells.
  Fu SL, Ma ZW, Yin L, Iannotti C, Lu PH, Xu XM. Fu SL, et al. Neuroscience. 2005;135(3):851-62. doi: 10.1016/j.neuroscience.2005.05.049. Neuroscience. 2005. PMID: 16213987
• In vitro expansion of a multipotent population of human neural progenitor cells.
  Carpenter MK, Cui X, Hu ZY, Jackson J, Sherman S, Seiger A, Wahlberg LU. Carpenter MK, et al. Exp Neurol. 1999 Aug;158(2):265-78. doi: 10.1006/exnr.1999.7098. Exp Neurol. 1999. PMID: 10415135
• The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development.
  Farkas LM, Huttner WB. Farkas LM, et al. Curr Opin Cell Biol. 2008 Dec;20(6):707-15. doi: 10.1016/j.ceb.2008.09.008. Epub 2008 Nov 5. Curr Opin Cell Biol. 2008. PMID: 18930817 Review.
• Research update: neurogenesis in adult brain and neuropsychiatric disorders.
  Elder GA, De Gasperi R, Gama Sosa MA. Elder GA, et al. Mt Sinai J Med. 2006 Nov;73(7):931-40. Mt Sinai J Med. 2006. PMID: 17195878 Review.

Cited by

• Brain-Derived Neurotrophic Factor Induces Cell Survival and the Migration of Murine Adult Hippocampal Precursor Cells During Differentiation In Vitro.
  Ortiz-López L, Vega-Rivera NM, Babu H, Ramírez-Rodríguez GB. Ortiz-López L, et al. Neurotox Res. 2017 Jan;31(1):122-135. doi: 10.1007/s12640-016-9673-x. Epub 2016 Sep 24. Neurotox Res. 2017. PMID: 27663583
• Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats.
  Sárvári M, Kalló I, Hrabovszky E, Solymosi N, Rodolosse A, Liposits Z. Sárvári M, et al. Front Cell Neurosci. 2016 Jun 10;10:149. doi: 10.3389/fncel.2016.00149. eCollection 2016. Front Cell Neurosci. 2016. PMID: 27375434 Free PMC article.
• An endogenous vitamin K-dependent mechanism regulates cell proliferation in the brain subventricular stem cell niche.
  Gely-Pernot A, Coronas V, Harnois T, Prestoz L, Mandairon N, Didier A, Berjeaud JM, Monvoisin A, Bourmeyster N, De Frutos PG, Philippe M, Benzakour O. Gely-Pernot A, et al. Stem Cells. 2012 Apr;30(4):719-31. doi: 10.1002/stem.1045. Stem Cells. 2012. PMID: 22290807 Free PMC article.
• Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells.
  Rhim JH, Luo X, Gao D, Xu X, Zhou T, Li F, Wang P, Wong ST, Xia X. Rhim JH, et al. Sci Rep. 2016 May 23;6:26547. doi: 10.1038/srep26547. Sci Rep. 2016. PMID: 27211495 Free PMC article.
• Differing in vitro survival dependency of mouse and rat NG2+ oligodendroglial progenitor cells.
  Horiuchi M, Lindsten T, Pleasure D, Itoh T. Horiuchi M, et al. J Neurosci Res. 2010 Apr;88(5):957-70. doi: 10.1002/jnr.22262. J Neurosci Res. 2010. PMID: 19908280 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science
  • Ovid Technologies, Inc.

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information