Neuronal Ca2+ signalling takes the local route - PubMed (original) (raw)
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Neuronal Ca2+ signalling takes the local route
G J Augustine et al. Curr Opin Neurobiol. 1992 Jun.
Abstract
The past year has seen several sets of experimental results demonstrate that fast, large and highly localized rises in intracellular Ca2+ concentration can occur in neurons. These results confirm previous theoretical predictions of acute spatial compartmentalization of Ca2+ signalling, and document a form of signalling that may occur whenever rapid and local signal processing is the goal. The dimensions involved present severe challenges for attempts to directly measure these signalling events.
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