Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number - PubMed (original) (raw)

Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids.

Trudler D, Ghatak S, Bula M, Parker J, Talantova M, Luevanos M, Labra S, Grabauskas T, Noveral SM, Teranaka M, Schahrer E, Dolatabadi N, Bakker C, Lopez K, Sultan A, Patel P, Chan A, Choi Y, Kawaguchi R, Stankiewicz P, Garcia-Bassets I, Kozbial P, Rosenfeld MG, Nakanishi N, Geschwind DH, Chan SF, Lin W, Schork NJ, Ambasudhan R, Lipton SA. Trudler D, et al. Mol Psychiatry. 2024 Sep 30. doi: 10.1038/s41380-024-02761-9. Online ahead of print. Mol Psychiatry. 2024. PMID: 39349966