Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element - PubMed (original) (raw)

Comparative Study

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element

P Leroy et al. Proc Natl Acad Sci U S A. 1991.

Abstract

We have characterized the promoter of the mouse retinoic acid receptor alpha 2 (mRAR-alpha 2) isoform. This promoter contains a retinoic acid response element (RARE) that closely resembles the RARE that is present in the RAR-beta 2 promoter. Moreover, RAR-alpha 2 and RAR-beta 2 proximal promoter sequences are similar to each other and generate transcripts whose respective start sites are located at similar positions. The RAR-alpha 2 RARE consists of two directly repeated 5'-GTTCA-3' motifs to which all three RARs (alpha, beta, and gamma) bind in vitro.

PubMed Disclaimer

References

1. 1. EMBO J. 1991 Aug;10(8):2223-30 - PubMed
2. 1. Nature. 1990 Jan 11;343(6254):177-80 - PubMed
3. 1. EMBO J. 1991 May;10(5):1149-58 - PubMed
4. 1. EMBO J. 1991 Jan;10(1):71-81 - PubMed
5. 1. EMBO J. 1991 Jan;10(1):59-69 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Atypon
  • Europe PubMed Central
  • PubMed Central

• Other Literature Sources

  • The Lens - Patent Citations

• Molecular Biology Databases

  • Guide to Pharmacology
  • Institute for Transcriptional Informatics
  • Mouse Genome Informatics (MGI)