How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde - PubMed (original) (raw)

Review

How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde

Michael J Gray et al. Infect Immun. 2006 May.

No abstract available

Figures

FIG. 1.

(A) Map of the L. monocytogenes plcA-prfA region, not drawn to scale. The heavy line at the bottom of the panel represents the DNA sequence, with gene coding regions indicated as boxes; the four lines above the gene coding region represent possible mRNA transcripts, including a 1.1-kb plcA transcript, a 2.1-kb plcA_-prfA bicistronic transcript, and 0.9- and 0.8-kb prfA transcripts (11, 13, 42, 67, 73, 91). Transcriptional start sites are indicated by bent arrows, and the plcA transcription terminator is indicated by a stem-loop. (B) DNA sequence of the prfA promoter region (46, 91). Triangles indicate transcriptional start sites identified for P1_prfA and P2_prfA_. The σA-dependent P1_prfA_ promoter is in boldface and underlined once. Two adjacent transcriptional start sites, possibly reflecting transcription from either the σA-dependent or σB-dependent promoter comprising the P2_prfA_ region, are marked by triangles (46). In the P2_prfA_ region, the σB-dependent promoter is in boldface and underlined twice; the proposed σA-dependent promoter is marked by double lines above the sequence, and the PrfA binding box (100), which is immediately upstream of the P2 promoter region, is marked by a dotted line beneath the sequence.

Cited by

Evolutionary dynamics of the accessory genome of Listeria monocytogenes.
den Bakker HC, Desjardins CA, Griggs AD, Peters JE, Zeng Q, Young SK, Kodira CD, Yandava C, Hepburn TA, Haas BJ, Birren BW, Wiedmann M. den Bakker HC, et al. PLoS One. 2013 Jun 25;8(6):e67511. doi: 10.1371/journal.pone.0067511. Print 2013. PLoS One. 2013. PMID: 23825666 Free PMC article.
Transcriptomic Analysis of the Adaptation of Listeria monocytogenes to Growth on Vacuum-Packed Cold Smoked Salmon.
Tang S, Orsi RH, den Bakker HC, Wiedmann M, Boor KJ, Bergholz TM. Tang S, et al. Appl Environ Microbiol. 2015 Oct;81(19):6812-24. doi: 10.1128/AEM.01752-15. Epub 2015 Jul 24. Appl Environ Microbiol. 2015. PMID: 26209664 Free PMC article.
Retrospective Use of Whole-Genome Sequencing Expands the Multicountry Outbreak Cluster of Listeria monocytogenes ST1247.
Mäesaar M, Mamede R, Elias T, Roasto M. Mäesaar M, et al. Int J Genomics. 2021 Apr 1;2021:6636138. doi: 10.1155/2021/6636138. eCollection 2021. Int J Genomics. 2021. PMID: 33869622 Free PMC article.
Maltose and maltodextrin utilization by Listeria monocytogenes depend on an inducible ABC transporter which is repressed by glucose.
Gopal S, Berg D, Hagen N, Schriefer EM, Stoll R, Goebel W, Kreft J. Gopal S, et al. PLoS One. 2010 Apr 27;5(4):e10349. doi: 10.1371/journal.pone.0010349. PLoS One. 2010. PMID: 20436965 Free PMC article.
Listeria monocytogenes {sigma}B has a small core regulon and a conserved role in virulence but makes differential contributions to stress tolerance across a diverse collection of strains.
Oliver HF, Orsi RH, Wiedmann M, Boor KJ. Oliver HF, et al. Appl Environ Microbiol. 2010 Jul;76(13):4216-32. doi: 10.1128/AEM.00031-10. Epub 2010 May 7. Appl Environ Microbiol. 2010. PMID: 20453120 Free PMC article.

References

1. Bassler, B. L. 2002. Small talk. Cell-to-cell communication in bacteria. Cell 109:421-424. - PubMed
1. Beauregard, K. E., K.-D. Lee, R. J. Collier, and J. A. Swanson. 1997. pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. J. Exp. Med. 186:1159-1163. - PMC - PubMed
1. Becker, L. A., M. S. Çetin, R. W. Hutkins, and A. K. Benson. 1998. Identification of the gene encoding the alternative sigma factor σB from Listeria monocytogenes and its role in osmotolerance. J. Bacteriol. 180:4547-4554. - PMC - PubMed
1. Begley, M., R. D. Sleator, C. G. M. Gahan, and C. Hill. 2005. Contribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes. Infect. Immun. 73:894-904. - PMC - PubMed
1. Behari, J., and P. Youngman. 1998. Regulation of hly expression in Listeria monocytogenes by carbon sources and pH occurs through separate mechanisms mediated by PrfA. Infect. Immun. 66:3635-3642. - PMC - PubMed

How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde - PubMed (original) (raw)