Direct intracranial, FMRI, and lesion evidence for the causal role of left inferotemporal cortex in reading - PubMed (original) (raw)
Case Reports
. 2006 Apr 20;50(2):191-204.
doi: 10.1016/j.neuron.2006.03.031.
Affiliations
- PMID: 16630832
- DOI: 10.1016/j.neuron.2006.03.031
Free article
Case Reports
Direct intracranial, FMRI, and lesion evidence for the causal role of left inferotemporal cortex in reading
Raphaël Gaillard et al. Neuron. 2006.
Free article
Abstract
Models of the "visual word form system" postulate that a left occipitotemporal region implements the automatic visual word recognition required for efficient reading. This theory was assessed in a patient in whom reading was explored with behavioral measures, fMRI, and intracranial local field potentials. Prior to surgery, when reading was normal, fMRI revealed a normal mosaic of ventral visual selectivity for words, faces, houses, and tools. Intracranial recordings demonstrated that the left occipitotemporal cortex responded with a short latency to conscious but also to subliminal words. Surgery removed a small portion of word-responsive occipitotemporal cortex overlapping with the word-specific fMRI activation. The patient developed a marked reading deficit, while recognition of other visual categories remained intact. Furthermore, in the post-surgery fMRI map of visual cortex, only word-specific activations disappeared. Altogether, these results provide direct evidence for the causal role of the left occipitotemporal cortex in the recognition of visual words.
Comment in
- Shades of Déjerine--forging a causal link between the visual word form area and reading.
Martin A. Martin A. Neuron. 2006 Apr 20;50(2):173-5. doi: 10.1016/j.neuron.2006.04.004. Neuron. 2006. PMID: 16630825 Review.
Similar articles
- Specialization within the ventral stream: the case for the visual word form area.
Cohen L, Dehaene S. Cohen L, et al. Neuroimage. 2004 May;22(1):466-76. doi: 10.1016/j.neuroimage.2003.12.049. Neuroimage. 2004. PMID: 15110040 - Recognition and reading aloud of kana and kanji word: an fMRI study.
Ino T, Nakai R, Azuma T, Kimura T, Fukuyama H. Ino T, et al. Brain Res Bull. 2009 Mar 16;78(4-5):232-9. doi: 10.1016/j.brainresbull.2008.11.008. Epub 2008 Dec 17. Brain Res Bull. 2009. PMID: 19100312 Clinical Trial. - Language experience shapes fusiform activation when processing a logographic artificial language: an fMRI training study.
Xue G, Chen C, Jin Z, Dong Q. Xue G, et al. Neuroimage. 2006 Jul 1;31(3):1315-26. doi: 10.1016/j.neuroimage.2005.11.055. Epub 2006 Apr 27. Neuroimage. 2006. PMID: 16644241 - Shades of Déjerine--forging a causal link between the visual word form area and reading.
Martin A. Martin A. Neuron. 2006 Apr 20;50(2):173-5. doi: 10.1016/j.neuron.2006.04.004. Neuron. 2006. PMID: 16630825 Review. - [Alexia without agraphia: an exemplary deficit, cherished by neuropsychologists].
Michel F. Michel F. Rev Neurol (Paris). 2008 May;164 Suppl 3:S73-6. doi: 10.1016/S0035-3787(08)73294-6. Rev Neurol (Paris). 2008. PMID: 18675050 Review. French.
Cited by
- Cracking the neural code for word recognition in convolutional neural networks.
Agrawal A, Dehaene S. Agrawal A, et al. PLoS Comput Biol. 2024 Sep 6;20(9):e1012430. doi: 10.1371/journal.pcbi.1012430. eCollection 2024 Sep. PLoS Comput Biol. 2024. PMID: 39241019 Free PMC article. - Taking the sublexical route: brain dynamics of reading in the semantic variant of primary progressive aphasia.
Borghesani V, Hinkley LBN, Ranasinghe KG, Thompson MMC, Shwe W, Mizuiri D, Lauricella M, Europa E, Honma S, Miller Z, Miller B, Vossel K, Henry MML, Houde JF, Gorno-Tempini ML, Nagarajan SS. Borghesani V, et al. Brain. 2020 Aug 1;143(8):2545-2560. doi: 10.1093/brain/awaa212. Brain. 2020. PMID: 32789455 Free PMC article. - New insights into the neural network mediating reading processes provided by cortico-subcortical electrical mapping.
Zemmoura I, Herbet G, Moritz-Gasser S, Duffau H. Zemmoura I, et al. Hum Brain Mapp. 2015 Jun;36(6):2215-30. doi: 10.1002/hbm.22766. Epub 2015 Feb 16. Hum Brain Mapp. 2015. PMID: 25684729 Free PMC article. - Neurally dissociable cognitive components of reading deficits in subacute stroke.
Boukrina O, Barrett AM, Alexander EJ, Yao B, Graves WW. Boukrina O, et al. Front Hum Neurosci. 2015 May 27;9:298. doi: 10.3389/fnhum.2015.00298. eCollection 2015. Front Hum Neurosci. 2015. PMID: 26082701 Free PMC article. - Enhanced category tuning revealed by intracranial electroencephalograms in high-order human visual areas.
Privman E, Nir Y, Kramer U, Kipervasser S, Andelman F, Neufeld MY, Mukamel R, Yeshurun Y, Fried I, Malach R. Privman E, et al. J Neurosci. 2007 Jun 6;27(23):6234-42. doi: 10.1523/JNEUROSCI.4627-06.2007. J Neurosci. 2007. PMID: 17553996 Free PMC article.