A dedicated Wnt secretion factor - PubMed (original) (raw)

Review

. 2006 May 5;125(3):432-3.

doi: 10.1016/j.cell.2006.04.018.

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• PMID: 16678089
• DOI: 10.1016/j.cell.2006.04.018

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Review

A dedicated Wnt secretion factor

Wendy Ching et al. Cell. 2006.

Free article

Abstract

The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.

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Comment on

• Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.
  Bänziger C, Soldini D, Schütt C, Zipperlen P, Hausmann G, Basler K. Bänziger C, et al. Cell. 2006 May 5;125(3):509-22. doi: 10.1016/j.cell.2006.02.049. Cell. 2006. PMID: 16678095
• Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.
  Bartscherer K, Pelte N, Ingelfinger D, Boutros M. Bartscherer K, et al. Cell. 2006 May 5;125(3):523-33. doi: 10.1016/j.cell.2006.04.009. Cell. 2006. PMID: 16678096

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