Analysis of the reactions used for the preparation of drug candidate molecules - PubMed (original) (raw)

Review

. 2006 Jun 21;4(12):2337-47.

doi: 10.1039/b602413k. Epub 2006 May 3.

Affiliations

• PMID: 16763676
• DOI: 10.1039/b602413k

Review

Analysis of the reactions used for the preparation of drug candidate molecules

John S Carey et al. Org Biomol Chem. 2006.

Abstract

The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.

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