Applications of total synthesis to problems in neurodegeneration: Fascinating chemistry along the way - PubMed (original) (raw)
Applications of total synthesis to problems in neurodegeneration: Fascinating chemistry along the way
Rebecca M Wilson et al. Acc Chem Res. 2006 Aug.
Abstract
The possibility for the application of organic synthesis to the discovery of new agents in combating neurodegenerative disorders is described. Our focus has been on agents derived from natural-product leads and natural products themselves prepared through total synthesis. Herein, we describe some of the chemistry as well as interesting observations made along the way.
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