Patterns of antimicrobial susceptibility in Michigan wildlife and bovine isolates of Mycobacterium bovis - PubMed (original) (raw)

Patterns of antimicrobial susceptibility in Michigan wildlife and bovine isolates of Mycobacterium bovis

Meighan Daly et al. J Vet Diagn Invest. 2006 Jul.

Abstract

The state of Michigan has recognized the presence of Mycobacterium bovis in its free-ranging white-tailed deer population since 1994. This endemic infection is primarily located in a 12-county area in the northeastern lower peninsula of Michigan. A statewide surveillance and eradication program of the disease has been in effect since 1994. Worldwide, Mycobacterium tuberculosis complex organisms have a known predilection toward development of antimicrobial resistance. The objective of this study was to investigate the antimicrobial susceptibility of M. bovis isolates from white-tailed deer in Michigan and detect any changes in susceptibility over time. M. bovis isolates from 2 fall hunting seasons (1999 and 2004) were used in this study. The fall season of 2004 marked the first documented case of direct transmission of M. bovis from a wild deer to a human in Michigan. Since M. bovis is a zoonotic disease, knowledge of susceptibility can expedite treatment options in humans. M. bovis isolates were obtained from 58 deer, 4 coyotes, 3 cattle, 2 raccoons, and 1 human case from the 2 years combined. Methods of susceptibility testing included 1% proportion agar plates and Bactec radiometric broth testing. M. bovis was found to be uniformly resistant to the antibiotic pyrazinamide; this resistance is common to all M. bovis isolates. No other antimicrobial resistance was found in any of the tested M. bovis isolates, which may be, in part, attributed to the lack of any significant treatment pressure in wildlife.

PubMed Disclaimer

Cited by

Antimicrobial Susceptibility Testing of Mycobacterium bovis Isolates from Michigan White-Tailed Deer during the 2009 Hunting Season.
Fitzgerald SD, Schooley AM, Berry DE, Kaneene JB. Fitzgerald SD, et al. Vet Med Int. 2010 Dec 2;2011:903683. doi: 10.4061/2011/903683. Vet Med Int. 2010. PMID: 21151656 Free PMC article.
Systemic tuberculosis by MYCOBACTERIUM BOVIS in a free-ranging MARSICAN brown bear (URSUS ARCTOS MARSICANUS): a Case report.
Fico R, Mariacher A, Franco A, Eleni C, Ciarrocca E, Pacciarini ML, Battisti A. Fico R, et al. BMC Vet Res. 2019 May 17;15(1):152. doi: 10.1186/s12917-019-1910-0. BMC Vet Res. 2019. PMID: 31101105 Free PMC article.
Trends of Mycobacterium bovis Isolation and First-Line Anti-tuberculosis Drug Susceptibility Profile: A Fifteen-Year Laboratory-Based Surveillance.
Bobadilla-del Valle M, Torres-González P, Cervera-Hernández ME, Martínez-Gamboa A, Crabtree-Ramirez B, Chávez-Mazari B, Ortiz-Conchi N, Rodríguez-Cruz L, Cervantes-Sánchez A, Gudiño-Enríquez T, Cinta-Severo C, Sifuentes-Osornio J, Ponce de León A. Bobadilla-del Valle M, et al. PLoS Negl Trop Dis. 2015 Sep 30;9(9):e0004124. doi: 10.1371/journal.pntd.0004124. eCollection 2015 Sep. PLoS Negl Trop Dis. 2015. PMID: 26421930 Free PMC article.
Detection of a streptomycin-resistant Mycobacterium bovis strain through antitubercular drug susceptibility testing of Tunisian Mycobacterium tuberculosis complex isolates from cattle.
Djemal SE, Camperio C, Armas F, Siala M, Smaoui S, Messadi-Akrout F, Gdoura R, Marianelli C. Djemal SE, et al. BMC Vet Res. 2018 Sep 29;14(1):296. doi: 10.1186/s12917-018-1623-9. BMC Vet Res. 2018. PMID: 30268120 Free PMC article.
Evaluation of Susceptibility to Antimycobacterial Drugs in Mycobacterium Tuberculosis Complex Strains Isolated from Cattle in Poland.
Krajewska-Wędzina M, Zabost A, Augustynowicz-Kopeć E, Weiner M, Szulowski K. Krajewska-Wędzina M, et al. J Vet Res. 2017 Apr 4;61(1):23-26. doi: 10.1515/jvetres-2017-0003. eCollection 2017 Mar. J Vet Res. 2017. PMID: 29978051 Free PMC article.

Patterns of antimicrobial susceptibility in Michigan wildlife and bovine isolates of Mycobacterium bovis - PubMed (original) (raw)