Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys - PubMed (original) (raw)
Multicenter Study
. 2006 Aug 26;368(9537):733-43.
doi: 10.1016/S0140-6736(06)69283-0.
Affiliations
- PMID: 16935684
- DOI: 10.1016/S0140-6736(06)69283-0
Multicenter Study
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys
M Innes Asher et al. Lancet. 2006.
Erratum in
- Lancet. 2007 Sep 29;370(9593):1128
Abstract
Background: Data for trends in prevalence of asthma, allergic rhinoconjunctivitis, and eczema over time are scarce. We repeated the International Study of Asthma and Allergies in Childhood (ISAAC) at least 5 years after Phase One, to examine changes in the prevalence of symptoms of these disorders.
Methods: For the ISAAC Phase Three study, between 2002 and 2003, we did a cross-sectional questionnaire survey of 193,404 children aged 6-7 years from 66 centres in 37 countries, and 304,679 children aged 13-14 years from 106 centres in 56 countries, chosen from a random sample of schools in a defined geographical area.
Findings: Phase Three was completed a mean of 7 years after Phase One. Most centres showed a change in prevalence of 1 or more SE for at least one disorder, with increases being twice as common as decreases, and increases being more common in the 6-7 year age-group than in the 13-14 year age-group, and at most levels of mean prevalence. An exception was asthma symptoms in the older age-group, in which decreases were more common at high prevalence. For both age-groups, more centres showed increases in all three disorders more often than showing decreases, but most centres had mixed changes.
Interpretation: The rise in prevalence of symptoms in many centres is concerning, but the absence of increases in prevalence of asthma symptoms for centres with existing high prevalence in the older age-group is reassuring. The divergent trends in prevalence of symptoms of allergic diseases form the basis for further research into the causes of such disorders.
Similar articles
- Changes over time in the relationship between symptoms of asthma, rhinoconjunctivitis and eczema: a global perspective from the International Study of Asthma and Allergies in Childhood (ISAAC).
Asher MI, Stewart AW, Wong G, Strachan DP, García-Marcos L, Anderson HR; ISAAC Phase Three Study Group. Asher MI, et al. Allergol Immunopathol (Madr). 2012 Sep-Oct;40(5):267-74. doi: 10.1016/j.aller.2011.11.004. Epub 2012 Jan 31. Allergol Immunopathol (Madr). 2012. PMID: 22297190 - Which population level environmental factors are associated with asthma, rhinoconjunctivitis and eczema? Review of the ecological analyses of ISAAC Phase One.
Asher MI, Stewart AW, Mallol J, Montefort S, Lai CK, Aït-Khaled N, Odhiambo J; ISAAC Phase One Study Group. Asher MI, et al. Respir Res. 2010 Jan 21;11(1):8. doi: 10.1186/1465-9921-11-8. Respir Res. 2010. PMID: 20092649 Free PMC article. Review. - Trends in worldwide asthma prevalence.
Asher MI, García-Marcos L, Pearce NE, Strachan DP. Asher MI, et al. Eur Respir J. 2020 Dec 24;56(6):2002094. doi: 10.1183/13993003.02094-2020. Print 2020 Dec. Eur Respir J. 2020. PMID: 32972987 Review.
Cited by
- Exploring genetic associations between metabolites and atopic dermatitis: insights from bidirectional Mendelian randomization analysis in European population.
He A, Hong Z, Zhao X, Li H, Xu Y, Xu Y, Jing Z, Ma H, Gong Z, Yang B, Zhou Q, Zheng F, Zhao X. He A, et al. Front Nutr. 2024 Sep 10;11:1451112. doi: 10.3389/fnut.2024.1451112. eCollection 2024. Front Nutr. 2024. PMID: 39318383 Free PMC article. - Versatile whey acidic protein four-disulfide core domain proteins: biology and role in diseases.
Wen Y, Jiang N, Wang Z, Xiao Y. Wen Y, et al. Front Cell Dev Biol. 2024 Sep 4;12:1459129. doi: 10.3389/fcell.2024.1459129. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 39296934 Free PMC article. Review. - Preclinical Development of SHR-1819, a Potent Humanized IL-4Rα Antibody for Treating Type 2 Inflammatory Diseases.
Zhao G, Wang Z, Zhang J, Lin Y, Zhou T, Liu K, Yang C, Liao C. Zhao G, et al. J Inflamm Res. 2024 Sep 14;17:6375-6388. doi: 10.2147/JIR.S471963. eCollection 2024. J Inflamm Res. 2024. PMID: 39296644 Free PMC article. - Roflumilast Cream, 0.15%, for Atopic Dermatitis in Adults and Children: INTEGUMENT-1 and INTEGUMENT-2 Randomized Clinical Trials.
Simpson EL, Eichenfield LF, Alonso-Llamazares J, Draelos ZD, Ferris LK, Forman SB, Gooderham M, Gonzalez ME, Hebert AA, Kircik LH, Lomaga M, Moore A, Papp KA, Prajapati VH, Hanna D, Snyder S, Krupa D, Burnett P, Almaraz E, Higham RC, Chu DH, Berk DR. Simpson EL, et al. JAMA Dermatol. 2024 Sep 18:e243121. doi: 10.1001/jamadermatol.2024.3121. Online ahead of print. JAMA Dermatol. 2024. PMID: 39292443 Free PMC article. - Trends of aeroallergen sensitization among children with respiratory allergy in Southern Thailand.
Sangchan T, Koosakulchai V, Sangsupawanich P, Srisuk B, Yuenyongviwat A. Sangchan T, et al. Asia Pac Allergy. 2024 Aug;14(3):103-107. doi: 10.5415/apallergy.0000000000000142. Epub 2024 Apr 4. Asia Pac Allergy. 2024. PMID: 39220568 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical