A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia - PubMed (original) (raw)

A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia

Isaac Schechter et al. Biol Psychiatry. 2006.

Abstract

Background: Schizophrenia is a neurocognitive disorder with a wide range of cognitive and sensory impairments. Early visual processing has been shown to be especially impaired. This article investigates the integrity of binocular depth perception (stereopsis) in schizophrenia.

Methods: Seventeen schizophrenia patients and 19 healthy control subjects were compared on the Graded Circles Stereo Test. Results of stereoacuity were compared between patients and control subjects using t test.

Results: Schizophrenia patients demonstrated significantly (p = .006) reduced stereoacuity (mean = 142 arcseconds) versus control subjects (mean = 55 arcseconds). At the normative level for adults, patients performed below chance.

Conclusions: These findings demonstrate an impairment of binocular depth perception and further confirm deficits of early visual processing in schizophrenia. Findings are discussed in context of magnocellular/dorsal stream processing with implications for visual processing and cognitive deficits.

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Figures

Fig. 1

A. Graph showing the group average waveforms for the high contrast (mixed M/P) condition over time for controls and patients with running _t_-test. B. Bar graph showing group average C1, P1, N1 and P2 component amplitudes with SEM for patients and controls. **P<.005, ***P<.001

Fig. 2

A. Graph showing the group average waveforms for the low contrast (M) condition over time for controls and patients with running _t_-test. B. Bar graph showing group average C1, P1, and N1 component amplitudes with SEM for patients and controls. ***P<.001

Fig. 3

A. Graph showing the group average waveforms for the chromatic contrast (P) condition over time for controls and patients with running _t_-test. B. Bar graph showing group average C1, P1, and N1 component amplitudes with SEM for patients and controls. **P<.005.

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A new dimension of sensory dysfunction: stereopsis deficits in schizophrenia - PubMed (original) (raw)