Towards neural circuit reconstruction with volume electron microscopy techniques - PubMed (original) (raw)
Review
Towards neural circuit reconstruction with volume electron microscopy techniques
Kevin L Briggman et al. Curr Opin Neurobiol. 2006 Oct.
Abstract
Electron microscopy is the only currently available technique with a resolution adequate to identify and follow every axon and dendrite in dense neuropil. Reconstructions of large volumes of neural tissue, necessary to reconstruct even local neural circuits, have, however, been inhibited by the daunting task of serially sectioning and reconstructing thousands of sections. Recent technological developments have improved the quality of volume electron microscopy data and automated its acquisition. This opens up the prospect of reconstructing almost complete invertebrate and sizable fractions of vertebrate nervous systems. Such reconstructions of complete neural wiring diagrams could rekindle the tradition of relating neural function to the underlying neuroanatomical circuitry.
Similar articles
- Volume electron microscopy for neuronal circuit reconstruction.
Briggman KL, Bock DD. Briggman KL, et al. Curr Opin Neurobiol. 2012 Feb;22(1):154-61. doi: 10.1016/j.conb.2011.10.022. Epub 2011 Nov 24. Curr Opin Neurobiol. 2012. PMID: 22119321 Review. - 3D structural imaging of the brain with photons and electrons.
Helmstaedter M, Briggman KL, Denk W. Helmstaedter M, et al. Curr Opin Neurobiol. 2008 Dec;18(6):633-41. doi: 10.1016/j.conb.2009.03.005. Epub 2009 Apr 9. Curr Opin Neurobiol. 2008. PMID: 19361979 Review. - Serial section electron tomography: a method for three-dimensional reconstruction of large structures.
Soto GE, Young SJ, Martone ME, Deerinck TJ, Lamont S, Carragher BO, Hama K, Ellisman MH. Soto GE, et al. Neuroimage. 1994 Jun;1(3):230-43. doi: 10.1006/nimg.1994.1008. Neuroimage. 1994. PMID: 9343574 - Contour-propagation algorithms for semi-automated reconstruction of neural processes.
Macke JH, Maack N, Gupta R, Denk W, Schölkopf B, Borst A. Macke JH, et al. J Neurosci Methods. 2008 Jan 30;167(2):349-57. doi: 10.1016/j.jneumeth.2007.07.021. Epub 2007 Aug 10. J Neurosci Methods. 2008. PMID: 17870180 - Knife-edge scanning microscopy for imaging and reconstruction of three-dimensional anatomical structures of the mouse brain.
Mayerich D, Abbott L, McCormick B. Mayerich D, et al. J Microsc. 2008 Jul;231(Pt 1):134-43. doi: 10.1111/j.1365-2818.2008.02024.x. J Microsc. 2008. PMID: 18638197
Cited by
- Building retinal connectomes.
Marc RE, Jones BW, Lauritzen JS, Watt CB, Anderson JR. Marc RE, et al. Curr Opin Neurobiol. 2012 Aug;22(4):568-74. doi: 10.1016/j.conb.2012.03.011. Epub 2012 Apr 11. Curr Opin Neurobiol. 2012. PMID: 22498714 Free PMC article. Review. - Neuronal tracing for connectomic studies.
Lu J. Lu J. Neuroinformatics. 2011 Sep;9(2-3):159-66. doi: 10.1007/s12021-011-9101-6. Neuroinformatics. 2011. PMID: 21340747 Review. - Automated detection and segmentation of synaptic contacts in nearly isotropic serial electron microscopy images.
Kreshuk A, Straehle CN, Sommer C, Koethe U, Cantoni M, Knott G, Hamprecht FA. Kreshuk A, et al. PLoS One. 2011;6(10):e24899. doi: 10.1371/journal.pone.0024899. Epub 2011 Oct 21. PLoS One. 2011. PMID: 22031814 Free PMC article. - Structural properties of the Caenorhabditis elegans neuronal network.
Varshney LR, Chen BL, Paniagua E, Hall DH, Chklovskii DB. Varshney LR, et al. PLoS Comput Biol. 2011 Feb 3;7(2):e1001066. doi: 10.1371/journal.pcbi.1001066. PLoS Comput Biol. 2011. PMID: 21304930 Free PMC article. - SEGMENTATION OF MITOCHONDRIA IN ELECTRON MICROSCOPY IMAGES USING ALGEBRAIC CURVES.
Seyedhosseini M, Ellisman MH, Tasdizen T. Seyedhosseini M, et al. Proc IEEE Int Symp Biomed Imaging. 2013;2013:860-863. doi: 10.1109/ISBI.2013.6556611. Proc IEEE Int Symp Biomed Imaging. 2013. PMID: 25132915 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources