Mechanisms for recovery of motor function following cortical damage - PubMed (original) (raw)
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Mechanisms for recovery of motor function following cortical damage
Randolph J Nudo. Curr Opin Neurobiol. 2006 Dec.
Abstract
Recent studies of focal injury to the cerebral cortex have demonstrated that the remaining, intact tissue undergoes structural and functional changes that could play a substantial role in neurological recovery. New information regarding the molecular and cellular environment in the adjacent, intact tissue has suggested that waves of growth promotion and inhibition modulate the self-repair processes of the brain. Furthermore, recent studies have documented widespread neurophysiological and neuroanatomical changes in regions remote from a focal cortical injury, suggesting that entire cortical networks participate in the recovery process.
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