Cloning and sequencing of human FSH receptor cDNA - PubMed (original) (raw)

Comparative Study

. 1991 Mar 29;175(3):1125-30.

doi: 10.1016/0006-291x(91)91682-3.

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Comparative Study

Cloning and sequencing of human FSH receptor cDNA

T Minegishi et al. Biochem Biophys Res Commun. 1991.

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Abstract

We have isolated and sequenced a cDNA encoding the follicle stimulating hormone (FSH) receptor. The deduced amino acid sequence (678 residues) containing seven putative transmembrane segments which displays sequence similarity to G protein-coupled receptors. The receptor consists of 359 residue extracellular domain which contains four N-linked glycosylation sites. While the protein is 89% identical overall with the previously cloned rat FSH receptor, the most highly conserved regions are the putative transmembrane segments (95% similarity).

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