The receptors and cells for mammalian taste - PubMed (original) (raw)
Review
. 2006 Nov 16;444(7117):288-94.
doi: 10.1038/nature05401.
Affiliations
- PMID: 17108952
- DOI: 10.1038/nature05401
Review
The receptors and cells for mammalian taste
Jayaram Chandrashekar et al. Nature. 2006.
Abstract
The emerging picture of taste coding at the periphery is one of elegant simplicity. Contrary to what was generally believed, it is now clear that distinct cell types expressing unique receptors are tuned to detect each of the five basic tastes: sweet, sour, bitter, salty and umami. Importantly, receptor cells for each taste quality function as dedicated sensors wired to elicit stereotypic responses.
Similar articles
- Taste information derived from T1R-expressing taste cells in mice.
Yoshida R, Ninomiya Y. Yoshida R, et al. Biochem J. 2016 Mar 1;473(5):525-36. doi: 10.1042/BJ20151015. Biochem J. 2016. PMID: 26912569 Review. - Taste perception: from the tongue to the testis.
Li F. Li F. Mol Hum Reprod. 2013 Jun;19(6):349-60. doi: 10.1093/molehr/gat009. Epub 2013 Feb 18. Mol Hum Reprod. 2013. PMID: 23423265 Review. - How taste works: cells, receptors and gustatory perception.
Kikut-Ligaj D, Trzcielińska-Lorych J. Kikut-Ligaj D, et al. Cell Mol Biol Lett. 2015 Dec;20(5):699-716. doi: 10.1515/cmble-2015-0042. Cell Mol Biol Lett. 2015. PMID: 26447485 Review. - Taste transductions in taste receptor cells: basic tastes and moreover.
Iwata S, Yoshida R, Ninomiya Y. Iwata S, et al. Curr Pharm Des. 2014;20(16):2684-92. doi: 10.2174/13816128113199990575. Curr Pharm Des. 2014. PMID: 23886388 Review. - Clinical Role of Extraoral Bitter Taste Receptors.
Jeruzal-Świątecka J, Fendler W, Pietruszewska W. Jeruzal-Świątecka J, et al. Int J Mol Sci. 2020 Jul 21;21(14):5156. doi: 10.3390/ijms21145156. Int J Mol Sci. 2020. PMID: 32708215 Free PMC article. Review.
Cited by
- In vivo Calcium Imaging of Mouse Geniculate Ganglion Neuron Responses to Taste Stimuli.
Fowler BE, Macpherson LJ. Fowler BE, et al. J Vis Exp. 2021 Feb 11;(168):10.3791/62172. doi: 10.3791/62172. J Vis Exp. 2021. PMID: 33645563 Free PMC article. - Regulation of bitter taste responses by tumor necrosis factor.
Feng P, Jyotaki M, Kim A, Chai J, Simon N, Zhou M, Bachmanov AA, Huang L, Wang H. Feng P, et al. Brain Behav Immun. 2015 Oct;49:32-42. doi: 10.1016/j.bbi.2015.04.001. Epub 2015 Apr 21. Brain Behav Immun. 2015. PMID: 25911043 Free PMC article. - High salt recruits aversive taste pathways.
Oka Y, Butnaru M, von Buchholtz L, Ryba NJ, Zuker CS. Oka Y, et al. Nature. 2013 Feb 28;494(7438):472-5. doi: 10.1038/nature11905. Epub 2013 Feb 13. Nature. 2013. PMID: 23407495 Free PMC article. - Salt Sensation and Regulation.
Puri S, Lee Y. Puri S, et al. Metabolites. 2021 Mar 17;11(3):175. doi: 10.3390/metabo11030175. Metabolites. 2021. PMID: 33802977 Free PMC article. Review. - Drosophila TRP channels and animal behavior.
Fowler MA, Montell C. Fowler MA, et al. Life Sci. 2013 Mar 19;92(8-9):394-403. doi: 10.1016/j.lfs.2012.07.029. Epub 2012 Aug 1. Life Sci. 2013. PMID: 22877650 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources