Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task - PubMed (original) (raw)

. 2007 Jun;179(4):643-53.

doi: 10.1007/s00221-006-0822-y. Epub 2007 Jan 10.

Affiliations

• PMID: 17216152
• DOI: 10.1007/s00221-006-0822-y

Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task

Marc Wittmann et al. Exp Brain Res. 2007 Jun.

Abstract

Delay discounting refers to the fact that an immediate reward is valued more than the same reward if it occurs some time in the future. To examine the neural substrates underlying this process, we studied 13 healthy volunteers who repeatedly had to decide between an immediate and parametrically varied delayed hypothetical reward using a delay discounting task during event-related functional magnetic resonance imaging. Subject's preference judgments resulted in different discounting slopes for shorter (<1 year) and for longer (> or =1 year) delays. Neural activation associated with the shorter delays relative to the longer delays was associated with increased activation in the head of the left caudate nucleus and putamen. When individuals selected the delayed relative to the immediate reward, a strong activation was found in bilateral posterior insular cortex. Several brain areas including the left caudate nucleus showed a correlation between the behaviorally determined discounting and brain activation for the contrast of intervals with delays <1 and > or =1 year. These results suggest that (1) the posterior insula, which is a critical component of the decision-making neural network, is involved in delaying gratification and (2) the degree of neural activation in the striatum, which plays a fundamental role in reward prediction and in time estimation, may code for the time delay.

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References

1. 1. J Exp Psychol Gen. 1999 Mar;128(1):78-87 - PubMed
2. 1. Exp Clin Psychopharmacol. 1998 Aug;6(3):292-305 - PubMed
3. 1. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2005 Mar;191(3):201-11 - PubMed
4. 1. Exp Brain Res. 1998 Dec;123(4):439-48 - PubMed
5. 1. Neuroimage. 2000 Jul;12(1):20-7 - PubMed

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