Nociception and TRP channels - PubMed (original) (raw)

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Nociception and TRP channels

M Tominaga. Handb Exp Pharmacol. 2007.

Abstract

Pain is initiated when noxious stimuli excite the peripheral terminals of specialized primary afferent neurons called nociceptors. Many molecules are involved in conversion of the noxious stimuli to the electrical signals in the nociceptor endings. Among them, TRP channels play important roles in detecting noxious stimuli.

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