Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER - PubMed (original) (raw)

Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER

P W Ingham et al. Genetics. 1985 Nov.

Abstract

Mutations of the hairy locus in Drosophila may affect both adult chaeta differentiation and embryonic segmentation. In an effort to understand this phenotypic complexity, we have analyzed 30 mutant alleles of the locus. We find that the alleles fall into four groups according to their complementation properties, suggesting a structurally complex locus in which two distinct functions share a common coding region.

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References

1. 1. Cell. 1982 Jul;29(3):995-1004 - PubMed
2. 1. EMBO J. 1984 Mar;3(3):569-73 - PubMed
3. 1. EMBO J. 1982;1(3):307-10 - PubMed
4. 1. Hereditas. 1973;73(1):11-6 - PubMed

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