Translating animal research into clinical benefit - PubMed (original) (raw)

Editorial

Translating animal research into clinical benefit

Daniel G Hackam. BMJ. 2007.

Abstract

Poor methodological standards in animal studies mean that positive results rarely translate to the clinical domain

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Conflict of interest statement

Competing interests: None declared.

Comment in

• Studies in animals should be more like those in humans.
  Spiers AS. Spiers AS. BMJ. 2007 Feb 10;334(7588):274. doi: 10.1136/bmj.39115.419236.1F. BMJ. 2007. PMID: 17289696 Free PMC article. No abstract available.

Comment on

• Comparison of treatment effects between animal experiments and clinical trials: systematic review.
  Perel P, Roberts I, Sena E, Wheble P, Briscoe C, Sandercock P, Macleod M, Mignini LE, Jayaram P, Khan KS. Perel P, et al. BMJ. 2007 Jan 27;334(7586):197. doi: 10.1136/bmj.39048.407928.BE. Epub 2006 Dec 15. BMJ. 2007. PMID: 17175568 Free PMC article. Review.

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References

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2. 1. Perel P, Roberts I, Sena E, Wheble P, Briscoe C, Sandercock P, et al. Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ 2007. doi: <10.1136/bmj.39048.407928.BE> - DOI - PMC - PubMed
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