Receptors coupled to ionic channels: the glutamate receptor family - PubMed (original) (raw)
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Receptors coupled to ionic channels: the glutamate receptor family
G P Gasic et al. Curr Opin Neurobiol. 1991 Jun.
Abstract
Glutamate-gated ion channels belong to a complex family of receptors containing several pharmacological subtypes. They are thought to be essential for the acquisition of associative memory and for activity-dependent synaptogenesis, and have been implicated in several central nervous system diseases. Within the past year, molecular cloning of the first glutamate receptor channel and several related subunits has opened new approaches for understanding the basis of these important phenomena.
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