Inappropriate prescribing of proton pump inhibitors in primary care - PubMed (original) (raw)

Inappropriate prescribing of proton pump inhibitors in primary care

Bisanth Thushila Batuwitage et al. Postgrad Med J. 2007 Jan.

Abstract

Objectives: To determine if an educational intervention initiated in secondary care can influence prescribing of proton pump inhibitors (PPIs) in the community.

Methods: A prospective study of PPI use in patients admitted to medical wards in a university hospital. A simple educational intervention was employed to reduce inappropriate prescribing of PPIs in the community.

Results: In the pre-intervention analysis 66/271 (24%) patients were receiving treatment with a PPI prescribed in the community. In 36/66 (54%) patients the PPI had been prescribed inappropriately. Six months after the intervention 91/344 (26%) patients were prescribed a PPI in the community. In only 45 of these 91 (49%) patients was there a recommended indication.

Conclusion: The intervention used in this study had no effect on the proportion of patients taking a PPI at the time of hospital admission or on the appropriateness of prescribing in the community.

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Conflict of interest statement

There are no competing interests.

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References

1. 1. National Institute for Clinical Excellence Guidance on the use of proton pump inhibitors in the treatment of dyspepsia. July 2000
2. 1. National Institute for Clinical Excellence Management of dyspepsia in adults in primary care. August 2004, revised July 2005
3. 1. Pillans P I, Kubler P A, Radford J M.et al Concordance between use of proton pump inhibitors and prescribing guidelines. Med J Australia 200017216–18. - PubMed
4. 1. Naunton M, Peterson G M, Bleasel M D. Overuse of proton pump inhibitors. J Clin Pharm Ther 200025333–340. - PubMed
5. 1. Nardino R Vender R J, Herbert P N. Overuse of acid‐suppressive therapy in hospitalised patients. Am J Gastroenterol 2000953118–3122. - PubMed

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