Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria - PubMed (original) (raw)

doi: 10.1039/b613319c. Epub 2006 Oct 24.

Affiliations

• PMID: 17299629
• DOI: 10.1039/b613319c

Synthesis of rigidly-linked vancomycin dimers and their in vivo efficacy against resistant bacteria

Jun Lu et al. Chem Commun (Camb). 2007.

Abstract

A novel and efficient avenue for the preparation of dimeric vancomycins is described, and the dimers exhibited excellent antibacterial activities in the murine infection model.

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