Odor cues during slow-wave sleep prompt declarative memory consolidation - PubMed (original) (raw)
. 2007 Mar 9;315(5817):1426-9.
doi: 10.1126/science.1138581.
Affiliations
- PMID: 17347444
- DOI: 10.1126/science.1138581
Odor cues during slow-wave sleep prompt declarative memory consolidation
Björn Rasch et al. Science. 2007.
Abstract
Sleep facilitates memory consolidation. A widely held model assumes that this is because newly encoded memories undergo covert reactivation during sleep. We cued new memories in humans during sleep by presenting an odor that had been presented as context during prior learning, and so showed that reactivation indeed causes memory consolidation during sleep. Re-exposure to the odor during slow-wave sleep (SWS) improved the retention of hippocampus-dependent declarative memories but not of hippocampus-independent procedural memories. Odor re-exposure was ineffective during rapid eye movement sleep or wakefulness or when the odor had been omitted during prior learning. Concurring with these findings, functional magnetic resonance imaging revealed significant hippocampal activation in response to odor re-exposure during SWS.
Comment in
- Neuroscience. Hunting for meaning after midnight.
Miller G. Miller G. Science. 2007 Mar 9;315(5817):1360-3. doi: 10.1126/science.315.5817.1360. Science. 2007. PMID: 17347425 No abstract available.
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