Immune responses to AAV capsid: are mice not humans after all? - PubMed (original) (raw)

Comment

Immune responses to AAV capsid: are mice not humans after all?

Roland W Herzog. Mol Ther. 2007 Apr.

Free article

No abstract available

PubMed Disclaimer

Comment on

• Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes.
  Li H, Murphy SL, Giles-Davis W, Edmonson S, Xiang Z, Li Y, Lasaro MO, High KA, Ertl HC. Li H, et al. Mol Ther. 2007 Apr;15(4):792-800. doi: 10.1038/sj.mt.6300090. Epub 2007 Jan 23. Mol Ther. 2007. PMID: 17245353

Similar articles

• Pre-existing AAV capsid-specific CD8+ T cells are unable to eliminate AAV-transduced hepatocytes.
  Li H, Murphy SL, Giles-Davis W, Edmonson S, Xiang Z, Li Y, Lasaro MO, High KA, Ertl HC. Li H, et al. Mol Ther. 2007 Apr;15(4):792-800. doi: 10.1038/sj.mt.6300090. Epub 2007 Jan 23. Mol Ther. 2007. PMID: 17245353
• Hemophilia Gene Therapy: Caught Between a Cure and an Immune Response.
  Herzog RW. Herzog RW. Mol Ther. 2015 Sep;23(9):1411-2. doi: 10.1038/mt.2015.135. Mol Ther. 2015. PMID: 26321180 Free PMC article. No abstract available.
• Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B.
  Rogers GL, Martino AT, Zolotukhin I, Ertl HC, Herzog RW. Rogers GL, et al. J Transl Med. 2014 Jan 25;12:25. doi: 10.1186/1479-5876-12-25. J Transl Med. 2014. PMID: 24460861 Free PMC article.
• Complexity of immune responses to AAV transgene products - Example of factor IX.
  Herzog RW. Herzog RW. Cell Immunol. 2019 Aug;342:103658. doi: 10.1016/j.cellimm.2017.05.006. Epub 2017 May 29. Cell Immunol. 2019. PMID: 28645365 Free PMC article. Review.
• Technology evaluation: AAV factor IX gene therapy, Avigen Inc.
  Fabb SA, Dickson JG. Fabb SA, et al. Curr Opin Mol Ther. 2000 Oct;2(5):601-6. Curr Opin Mol Ther. 2000. PMID: 11249763 Review.

Cited by

• Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?
  Grimm D, Kay MA. Grimm D, et al. J Clin Invest. 2007 Dec;117(12):3633-41. doi: 10.1172/JCI34129. J Clin Invest. 2007. PMID: 18060021 Free PMC article. Review.
• Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.
  Markusic DM, Herzog RW. Markusic DM, et al. J Genet Syndr Gene Ther. 2012 Jan 18;1:1-9. doi: 10.4172/2157-7412.S1-009. J Genet Syndr Gene Ther. 2012. PMID: 23565343 Free PMC article.
• AAV vector biology in primates: finding the missing link?
  Herzog RW, Davidoff AM, Markusic DM, Nathwani AC. Herzog RW, et al. Mol Ther. 2011 Nov;19(11):1923-4. doi: 10.1038/mt.2011.218. Mol Ther. 2011. PMID: 22051598 Free PMC article. No abstract available.
• Targeted gene therapy for the treatment of heart failure.
  Rapti K, Chaanine AH, Hajjar RJ. Rapti K, et al. Can J Cardiol. 2011 May-Jun;27(3):265-83. doi: 10.1016/j.cjca.2011.02.005. Can J Cardiol. 2011. PMID: 21601767 Free PMC article. Review.
• Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder.
  Shay TF, Jang S, Brittain TJ, Chen X, Walker B, Tebbutt C, Fan Y, Wolfe DA, Arokiaraj CM, Sullivan EE, Ding X, Wang TY, Lei Y, Chuapoco MR, Chou TF, Gradinaru V. Shay TF, et al. Nat Commun. 2024 Sep 8;15(1):7853. doi: 10.1038/s41467-024-52149-0. Nat Commun. 2024. PMID: 39245720 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database