Supportive-expressive group therapy for women with metastatic breast cancer: survival and psychosocial outcome from a randomized controlled trial - PubMed (original) (raw)
Randomized Controlled Trial
doi: 10.1002/pon.1185.
Affiliations
- PMID: 17385190
- DOI: 10.1002/pon.1185
Randomized Controlled Trial
Supportive-expressive group therapy for women with metastatic breast cancer: survival and psychosocial outcome from a randomized controlled trial
David W Kissane et al. Psychooncology. 2007 Apr.
Abstract
Background: Mixed reports exist about the impact of supportive-expressive group therapy (SEGT) on survival.
Methods: From 485 women with advanced breast cancer recruited between 1996-2002, 227 (47%) consented and were randomized within an average 10 months of cancer recurrence in a 2:1 ratio to intervention with 1 year or more of weekly SEGT plus three classes of relaxation therapy (147 women) or to control receiving three classes of relaxation therapy (80 women). The primary outcome was survival; psychosocial well-being was appraised secondarily. Analysis was by intention-to-treat.
Results: SEGT did not prolong survival (median survival 24.0 months in SEGT and 18.3 in controls; univariate hazard ratio for death 0.92 [95% CI, 0.69-1.26]; multivariate hazard ratio, 1.06 [95% CI, 0.74-1.51]). Significant predictors of survival were treatment with chemotherapy and hormone therapy (p<0.001), visceral metastases (p<0.001) and advanced disease at first diagnosis (p<0.05). SEGT ameliorated and prevented new DSM-IV depressive disorders (p = 0.002), reduced hopeless-helplessness (p = 0.004), trauma symptoms (p = 0.04) and improved social functioning (p = 0.03).
Conclusions: SEGT did not prolong survival. It improved quality of life, including treatment of and protection against depression.
Copyright (c) 2007 John Wiley & Sons, Ltd.
Comment in
- Psychotherapy does not promote survival (Kissane et al., 2007): now what?
Coyne JC, Hanisch LJ, Palmer SC. Coyne JC, et al. Psychooncology. 2007 Nov;16(11):1050-2. doi: 10.1002/pon.1285. Psychooncology. 2007. PMID: 17937383 Review. No abstract available.
Similar articles
- The effect of group psychosocial support on survival in metastatic breast cancer.
Goodwin PJ, Leszcz M, Ennis M, Koopmans J, Vincent L, Guther H, Drysdale E, Hundleby M, Chochinov HM, Navarro M, Speca M, Hunter J. Goodwin PJ, et al. N Engl J Med. 2001 Dec 13;345(24):1719-26. doi: 10.1056/NEJMoa011871. N Engl J Med. 2001. PMID: 11742045 Clinical Trial. - Effects of supportive-expressive group therapy on survival of patients with metastatic breast cancer: a randomized prospective trial.
Spiegel D, Butler LD, Giese-Davis J, Koopman C, Miller E, DiMiceli S, Classen CC, Fobair P, Carlson RW, Kraemer HC. Spiegel D, et al. Cancer. 2007 Sep 1;110(5):1130-8. doi: 10.1002/cncr.22890. Cancer. 2007. PMID: 17647221 Clinical Trial. - Effect of cognitive-existential group therapy on survival in early-stage breast cancer.
Kissane DW, Love A, Hatton A, Bloch S, Smith G, Clarke DM, Miach P, Ikin J, Ranieri N, Snyder RD. Kissane DW, et al. J Clin Oncol. 2004 Nov 1;22(21):4255-60. doi: 10.1200/JCO.2004.12.129. Epub 2004 Sep 27. J Clin Oncol. 2004. PMID: 15452189 Clinical Trial. - 259 Patients with DCIS of the breast applying USC/Van Nuys prognostic index: a retrospective review with long term follow up.
Di Saverio S, Catena F, Santini D, Ansaloni L, Fogacci T, Mignani S, Leone A, Gazzotti F, Gagliardi S, De Cataldis A, Taffurelli M. Di Saverio S, et al. Breast Cancer Res Treat. 2008 Jun;109(3):405-16. doi: 10.1007/s10549-007-9668-7. Epub 2007 Aug 9. Breast Cancer Res Treat. 2008. PMID: 17687650 Review. - The rationale and foundations of group psychotherapy for women with metastatic breast cancer.
Leszcz M, Goodwin PJ. Leszcz M, et al. Int J Group Psychother. 1998 Apr;48(2):245-73. doi: 10.1080/00207284.1998.11491538. Int J Group Psychother. 1998. PMID: 9563240 Review.
Cited by
- Global disparities in cancer supportive care: An international survey.
Chan A, Eng L, Jiang C, Dagsi M, Ke Y, Tanay M, Bergerot C, Dixit N, Gutiérrez AC, Velazquez AI, Islami F, Soto-Perez-de-Celis E. Chan A, et al. Cancer Med. 2024 Sep;13(17):e70234. doi: 10.1002/cam4.70234. Cancer Med. 2024. PMID: 39268694 Free PMC article. - Finding my tribe: a qualitative interview study of how people living with metastatic breast cancer perceive support groups.
Mackie GM, Boyle F, Lewis S, Smith AL. Mackie GM, et al. J Cancer Surviv. 2024 Jul 24. doi: 10.1007/s11764-024-01639-7. Online ahead of print. J Cancer Surviv. 2024. PMID: 39048845 - Feasibility of online managing cancer and living meaningfully (CALM) in Chinese patients with metastatic breast cancer: a pilot randomized control trial.
Zhang Y, Pang Y, He Y, You M, Tang L. Zhang Y, et al. Sci Rep. 2024 Feb 28;14(1):4892. doi: 10.1038/s41598-024-52574-7. Sci Rep. 2024. PMID: 38418478 Free PMC article. Clinical Trial. - Survival as a clinical outcome and its spiritual significance in a cohort of patients with advanced central pelvic neoplastic disease undergoing total pelvic evisceration: a poorly debated issue.
Macciò A, Sanna E, Piras R, Lavra F, Vallerino V, Maricosu G, Giglio E, Mura A, Tidore M, Madeddu C. Macciò A, et al. Front Med (Lausanne). 2023 Jun 9;10:1173687. doi: 10.3389/fmed.2023.1173687. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37359011 Free PMC article. - International adaptation of Meaning-Centered Psychotherapy for Latinos: Providers' views on pre-implementation.
Costas-Muñiz R, Torres-Blasco N, Castro-Figueroa EM, Claros M, Narang B, Galindo Vazquez O, Montaña F, Sanchez JC, Gany F. Costas-Muñiz R, et al. Implement Res Pract. 2022 May 2;3:26334895221096291. doi: 10.1177/26334895221096291. eCollection 2022 Jan-Dec. Implement Res Pract. 2022. PMID: 37091083 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical