Experience-dependent rescaling of entorhinal grids - PubMed (original) (raw)

doi: 10.1038/nn1905. Epub 2007 May 7.

Affiliations

• PMID: 17486102
• DOI: 10.1038/nn1905

Experience-dependent rescaling of entorhinal grids

Caswell Barry et al. Nat Neurosci. 2007 Jun.

Abstract

The firing pattern of entorhinal 'grid cells' is thought to provide an intrinsic metric for space. We report a strong experience-dependent environmental influence: the spatial scales of the grids (which are aligned and have fixed relative sizes within each animal) vary parametrically with changes to a familiar environment's size and shape. Thus grid scale reflects an interaction between intrinsic, path-integrative calculation of location and learned associations to the external environment.

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