A Bayesian evaluation of four immunological assays for the diagnosis of clinical cryptosporidiosis in calves - PubMed (original) (raw)
A Bayesian evaluation of four immunological assays for the diagnosis of clinical cryptosporidiosis in calves
Thomas Geurden et al. Vet J. 2008 Jun.
Abstract
A Bayesian approach was used to evaluate four immunological assays for the clinical diagnosis of cryptosporidiosis in calves: an immunofluorescence assay (IFA), two ELISA tests and an immunochromatographic (dipstick) assay. Faecal samples from 287 calves aged less than 6 weeks with clinical signs of gastrointestinal disease were examined for the presence of Cryptosporidium spp. The high prevalence (63%) of Cryptosporidium spp. indicated the relevance of this agent in the aetiology of diarrhoea in calves. All diagnostic assays were found to be relatively specific (IFA: 94.8%; Tetra ELISA: 95.9%; Techlab ELISA: 92.7%; dipstick assay: 91.5%) and sensitive (IFA: 97.4%; Tetra ELISA: 93.6%; Techlab ELISA: 95.4%; dipstick: 87.8%). Despite a lower sensitivity, the dipstick assay provided a practical alternative to laboratory diagnosis of clinical cryptosporidiosis in calves.
Similar articles
- A Bayesian approach for the evaluation of six diagnostic assays and the estimation of Cryptosporidium prevalence in dairy calves.
Geurden T, Berkvens D, Geldhof P, Vercruysse J, Claerebout E. Geurden T, et al. Vet Res. 2006 Sep-Oct;37(5):671-82. doi: 10.1051/vetres:2006029. Epub 2006 Jun 17. Vet Res. 2006. PMID: 16777038 - Estimation of diagnostic test characteristics and prevalence of Giardia duodenalis in dairy calves in Belgium using a Bayesian approach.
Geurden T, Claerebout E, Vercruysse J, Berkvens D. Geurden T, et al. Int J Parasitol. 2004 Sep;34(10):1121-7. doi: 10.1016/j.ijpara.2004.05.007. Int J Parasitol. 2004. PMID: 15380683 - An examination of the prevalence of and risk factors for shedding of Cryptosporidium spp. and Giardia spp. in cows and calves from western Canadian cow-calf herds.
Gow S, Waldner C. Gow S, et al. Vet Parasitol. 2006 Apr 15;137(1-2):50-61. doi: 10.1016/j.vetpar.2005.05.071. Epub 2006 Feb 10. Vet Parasitol. 2006. PMID: 16472921 - [Cryptosporidiosis: an emerging zoonosis].
Del Coco VF, Córdoba MA, Basualdo JA. Del Coco VF, et al. Rev Argent Microbiol. 2009 Jun-Sep;41(3):185-96. Rev Argent Microbiol. 2009. PMID: 19831318 Review. Spanish. - Cryptosporidium--biotechnological advances in the detection, diagnosis and analysis of genetic variation.
Jex AR, Smith HV, Monis PT, Campbell BE, Gasser RB. Jex AR, et al. Biotechnol Adv. 2008 Jul-Aug;26(4):304-17. doi: 10.1016/j.biotechadv.2008.02.003. Epub 2008 Mar 4. Biotechnol Adv. 2008. PMID: 18430539 Review.
Cited by
- Diagnosis and control of cryptosporidiosis in farm animals.
Aboelsoued D, Abdel Megeed KN. Aboelsoued D, et al. J Parasit Dis. 2022 Dec;46(4):1133-1146. doi: 10.1007/s12639-022-01513-2. Epub 2022 Jul 4. J Parasit Dis. 2022. PMID: 36457776 Free PMC article. Review. - Age-stratified Bayesian analysis to estimate sensitivity and specificity of four diagnostic tests for detection of Cryptosporidium oocysts in neonatal calves.
De Waele V, Berzano M, Berkvens D, Speybroeck N, Lowery C, Mulcahy GM, Murphy TM. De Waele V, et al. J Clin Microbiol. 2011 Jan;49(1):76-84. doi: 10.1128/JCM.01424-10. Epub 2010 Nov 3. J Clin Microbiol. 2011. PMID: 21048012 Free PMC article. - Association between passive immunity and health status of dairy calves under 30 days of age.
Lora I, Gottardo F, Contiero B, Dall Ava B, Bonfanti L, Stefani A, Barberio A. Lora I, et al. Prev Vet Med. 2018 Apr 1;152:12-15. doi: 10.1016/j.prevetmed.2018.01.009. Epub 2018 Feb 3. Prev Vet Med. 2018. PMID: 29559100 Free PMC article. - Advances in prevention and therapy of neonatal dairy calf diarrhoea: a systematical review with emphasis on colostrum management and fluid therapy.
Meganck V, Hoflack G, Opsomer G. Meganck V, et al. Acta Vet Scand. 2014 Nov 25;56(1):75. doi: 10.1186/s13028-014-0075-x. Acta Vet Scand. 2014. PMID: 25431305 Free PMC article. Review. - Molecular characterization of Giardia intestinalis and Cryptosporidium parvum from calves with diarrhoea in Austria and evaluation of point-of-care tests.
Lichtmannsperger K, Hinney B, Joachim A, Wittek T. Lichtmannsperger K, et al. Comp Immunol Microbiol Infect Dis. 2019 Oct;66:101333. doi: 10.1016/j.cimid.2019.101333. Epub 2019 Jul 12. Comp Immunol Microbiol Infect Dis. 2019. PMID: 31437689 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous