Enzyme markers to identify and characterize Opisthorchis viverrini in Thailand and Lao PDR - PubMed (original) (raw)

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Enzyme markers to identify and characterize Opisthorchis viverrini in Thailand and Lao PDR

Weerachai Saijuntha et al. Southeast Asian J Trop Med Public Health. 2006.

Abstract

We conducted an allozyme electrophoretic study to explore potential enzyme markers to distinguish Opisthorchis viverrini in Thailand and Lao PDR. Twenty-eight enzymes encoding presumptive 32 loci were established. The enzymes glucose-6-phosphate dehydrogenase and pyruvate kinase were diagnostic between two geographically separate isolates from Thailand. Twelve enzymes, ie, aconitate hydratase, aldolase, creatine kinase, enolase, esterases, fumarate hydratase, aspartate aminotransferase, glucose-phosphate isomerase, alanine aminotransferase, isocitrate dehydrogenase, malic enzyme, and pyruvate kinase, also provided diagnostic markers for these two isolates from Thailand and one isolate from Lao PDR.

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