Contribution of a new mutation in parE to quinolone resistance in extended-spectrum-beta-lactamase-producing Escherichia coli isolates - PubMed (original) (raw)

Contribution of a new mutation in parE to quinolone resistance in extended-spectrum-beta-lactamase-producing Escherichia coli isolates

Antonio Sorlozano et al. J Clin Microbiol. 2007 Aug.

Abstract

Mutations in the quinolone resistance-determining regions of gyrA, gyrB, parC, and parE were studied in 30 fluoroquinolone-resistant clinical isolates of Escherichia coli producing extended-spectrum beta-lactamases. Ten isolates showed a mutation in parE that was significantly associated with an increase in the MIC for fluoroquinolones.

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References

    1. Alos, J. I. 2003. Quinolones. Enferm. Infecc. Microbiol. Clin. 21**:**261-267. -PubMed
    1. Clinical and Laboratory Standards Institute. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 7th ed. Approved standard. CLSI publication M7-A7. Clinical and Laboratory Standards Institute, Wayne, Pa.
    1. Daza, R., J. Gutierrez, and G. Piedrota. 2001. Antibiotic susceptibility of bacterial strains isolated from patients with community-acquired urinary tract infections. Int. J. Antimicrob. Agents 18**:**211-215. -PubMed
    1. Everett, M. J., Y. F. Jin, V. Ricci, and L. J. Piddock. 1996. Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Antimicrob. Agents Chemother. 40**:**2380-2386. -PMC -PubMed
    1. Hernandez, J. R., A. Pascual, R. Canton, L. Martinez-Martinez, and Grupo de Estudio de Infeccion Hospitalaria. 2003. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Spanish hospitals (GEIH-BLEE Project 2002). Enferm. Infecc. Microbiol. Clin. 21**:**77-82. -PubMed

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