Tracing genetic change over time using nuclear SNPs in ancient and modern cattle - PubMed (original) (raw)
Comparative Study
Tracing genetic change over time using nuclear SNPs in ancient and modern cattle
E M Svensson et al. Anim Genet. 2007 Aug.
Abstract
Ancient DNA has the potential of adding the dimension of time to genetic studies. With a suitable sample set it should be possible to follow genetic changes over time as they occur. To date, only a limited number of ancient DNA studies that cover a large time span have been published, and all of these studies have used mitochondrial DNA. Here, we explore SNP typing as a way to access ancient coding nuclear genes. By targeting fragments of minimal size, we typed three polymorphic sites in 111 ancient cattle remains spanning some 4000 years. We showed that there has been a decrease in heterozygosity over time, especially since the late Middle Ages. We conclude that SNPs can be used to generate a time series for nuclear markers from ancient material, and thereby to study selection on genes over time.
Similar articles
- Single nucleotide polymorphisms in the open reading frame of the stearoyl-CoA desaturase gene and resulting genetic variants in Canadian Holstein and Jersey cows.
Kgwatalala PM, Ibeagha-Awemu EM, Hayes JF, Zhao X. Kgwatalala PM, et al. DNA Seq. 2007 Oct;18(5):357-62. doi: 10.1080/10425170701291921. DNA Seq. 2007. PMID: 17654011 - Estimation of genetic diversity in Siri cattle from India.
Sharma R, Pandey AK, Singh Y, Mishra BP, Singh PK, Singh G. Sharma R, et al. Genetika. 2008 Nov;44(11):1532-8. Genetika. 2008. PMID: 19137737 - Genes on bovine chromosome 18 associated with bilateral convergent strabismus with exophthalmos in German Brown cattle.
Fink S, Mömke S, Wöhlke A, Distl O. Fink S, et al. Mol Vis. 2008 Sep 22;14:1737-51. Mol Vis. 2008. PMID: 18836565 Free PMC article. - Discovery, characterization and validation of single nucleotide polymorphisms within 206 bovine genes that may be considered as candidate genes for beef production and quality.
Williams JL, Dunner S, Valentini A, Mazza R, Amarger V, Checa ML, Crisà A, Razzaq N, Delourme D, Grandjean F, Marchitelli C, García D, Gomez RP, Negrini R, Marsan PA, Levéziel H. Williams JL, et al. Anim Genet. 2009 Aug;40(4):486-91. doi: 10.1111/j.1365-2052.2009.01874.x. Epub 2009 Apr 16. Anim Genet. 2009. PMID: 19397516 - Accuracy of marker-assisted selection with single markers and marker haplotypes in cattle.
Hayes BJ, Chamberlain AJ, McPartlan H, Macleod I, Sethuraman L, Goddard ME. Hayes BJ, et al. Genet Res. 2007 Aug;89(4):215-20. doi: 10.1017/S0016672307008865. Genet Res. 2007. PMID: 18208627
Cited by
- Spotted phenotypes in horses lost attractiveness in the Middle Ages.
Wutke S, Benecke N, Sandoval-Castellanos E, Döhle HJ, Friederich S, Gonzalez J, Hallsson JH, Hofreiter M, Lõugas L, Magnell O, Morales-Muniz A, Orlando L, Pálsdóttir AH, Reissmann M, Ruttkay M, Trinks A, Ludwig A. Wutke S, et al. Sci Rep. 2016 Dec 7;6:38548. doi: 10.1038/srep38548. Sci Rep. 2016. PMID: 27924839 Free PMC article. - Goth migration induced changes in the matrilineal genetic structure of the central-east European population.
Stolarek I, Handschuh L, Juras A, Nowaczewska W, Kóčka-Krenz H, Michalowski A, Piontek J, Kozlowski P, Figlerowicz M. Stolarek I, et al. Sci Rep. 2019 May 1;9(1):6737. doi: 10.1038/s41598-019-43183-w. Sci Rep. 2019. PMID: 31043639 Free PMC article. - Farmers without borders-genetic structuring in century old barley (Hordeum vulgare).
Forsberg NE, Russell J, Macaulay M, Leino MW, Hagenblad J. Forsberg NE, et al. Heredity (Edinb). 2015 Feb;114(2):195-206. doi: 10.1038/hdy.2014.83. Epub 2014 Sep 17. Heredity (Edinb). 2015. PMID: 25227257 Free PMC article. - Development and Optimization of a Silica Column-Based Extraction Protocol for Ancient DNA.
Dehasque M, Pečnerová P, Kempe Lagerholm V, Ersmark E, Danilov GK, Mortensen P, Vartanyan S, Dalén L. Dehasque M, et al. Genes (Basel). 2022 Apr 13;13(4):687. doi: 10.3390/genes13040687. Genes (Basel). 2022. PMID: 35456493 Free PMC article. - Single Nucleotide Polymorphisms, Gene Expression and Economic Evaluation of Parameters Associated with Mastitis Susceptibility in European Cattle Breeds.
Ateya AI, Ibrahim SS, Al-Sharif MM. Ateya AI, et al. Vet Sci. 2022 Jun 14;9(6):294. doi: 10.3390/vetsci9060294. Vet Sci. 2022. PMID: 35737346 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources