Moving with or without will: functional neural correlates of alien hand syndrome - PubMed (original) (raw)
Case Reports
doi: 10.1002/ana.21173.
Affiliations
- PMID: 17638304
- DOI: 10.1002/ana.21173
Case Reports
Moving with or without will: functional neural correlates of alien hand syndrome
Frédéric Assal et al. Ann Neurol. 2007 Sep.
Abstract
Alien hand syndrome is a rare neurological disorder in which movements are performed without conscious will. By using functional magnetic resonance imaging in a patient with alien hand syndrome after right parietal lesion, we could identify brain regions activated during involuntary or voluntary actions with the affected left hand. Alien hand movements involved a selective activation of contralateral primary motor cortex (M1), presumably released from conscious control by intentional planning systems. By contrast, voluntary movements activated a distributed network implicating not only the contralateral right M1 and premotor cortex but also the left inferior frontal gyrus, suggesting an important role of the dominant hemisphere in organizing willed actions.
Similar articles
- Cortical connectivity after subcortical stroke assessed with functional magnetic resonance imaging.
Grefkes C, Nowak DA, Eickhoff SB, Dafotakis M, Küst J, Karbe H, Fink GR. Grefkes C, et al. Ann Neurol. 2008 Feb;63(2):236-46. doi: 10.1002/ana.21228. Ann Neurol. 2008. PMID: 17896791 - Alterations in voluntary movement execution in Huntington's disease are related to the dominant motor system: evidence from event-related potentials.
Beste C, Konrad C, Saft C, Ukas T, Andrich J, Pfleiderer B, Hausmann M, Falkenstein M. Beste C, et al. Exp Neurol. 2009 Mar;216(1):148-57. doi: 10.1016/j.expneurol.2008.11.018. Epub 2008 Dec 10. Exp Neurol. 2009. PMID: 19111540 - [Involuntary motor activity or alien hand syndrome following ischemic lesion sparing medial frontal cortex].
Pageot N, Nighoghossian N, Derex L, Bascoulergue Y, Trouilias P. Pageot N, et al. Rev Neurol (Paris). 1997 Jun;153(5):339-43. Rev Neurol (Paris). 1997. PMID: 9296169 French. - [Alien hand syndrome: a review of the literature].
Hidalgo-Borrajo R, Belaunzaran-Mendizábal J, Hernáez-Goñi P, Tirapu-Ustárroz J, Luna-Lario P. Hidalgo-Borrajo R, et al. Rev Neurol. 2009 May 16-31;48(10):534-9. Rev Neurol. 2009. PMID: 19434588 Review. Spanish. - [A case of alien hand syndrome after right posterior cerebral artery territory infarction].
Kato H, Iijima M, Hiroi A, Kubo M, Uchigata M. Kato H, et al. Rinsho Shinkeigaku. 2003 Aug;43(8):487-90. Rinsho Shinkeigaku. 2003. PMID: 14658401 Review. Japanese.
Cited by
- Long-lasting diagonistic dyspraxia suppressed by rTMS applied to the right motor cortex.
Sellal F, Cretin B, Musacchio M, Berthel MC, Carelli G, Michel JM. Sellal F, et al. J Neurol. 2019 Mar;266(3):631-635. doi: 10.1007/s00415-018-09178-9. Epub 2019 Jan 10. J Neurol. 2019. PMID: 30631917 - Alien hand syndrome: neural correlates of movements without conscious will.
Schaefer M, Heinze HJ, Galazky I. Schaefer M, et al. PLoS One. 2010 Dec 13;5(12):e15010. doi: 10.1371/journal.pone.0015010. PLoS One. 2010. PMID: 21179436 Free PMC article. - Impairment of a parieto-premotor network specialized for handwriting in writer's cramp.
Gallea C, Horovitz SG, Najee-Ullah M', Hallett M. Gallea C, et al. Hum Brain Mapp. 2016 Dec;37(12):4363-4375. doi: 10.1002/hbm.23315. Epub 2016 Jul 28. Hum Brain Mapp. 2016. PMID: 27466043 Free PMC article. - Exaggerated object affordance and absent automatic inhibition in alien hand syndrome.
McBride J, Sumner P, Jackson SR, Bajaj N, Husain M. McBride J, et al. Cortex. 2013 Sep;49(8):2040-54. doi: 10.1016/j.cortex.2013.01.004. Epub 2013 Jan 23. Cortex. 2013. PMID: 23433243 Free PMC article. - Alien hand syndrome - a rare presentation of stroke.
Le K, Zhang C, Greisman L. Le K, et al. J Community Hosp Intern Med Perspect. 2020 May 21;10(2):149-150. doi: 10.1080/20009666.2020.1756610. J Community Hosp Intern Med Perspect. 2020. PMID: 32850052 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical