Presentation, clinical course, and outcome of childhood stroke - PubMed (original) (raw)
Presentation, clinical course, and outcome of childhood stroke
M J Lanska et al. Pediatr Neurol. 1991 Sep-Oct.
Abstract
We reviewed the presentations, clinical courses, and outcomes of 42 children with unilateral hemispheric stroke. Infants with strokes identified within the first few days of life usually presented with seizures. These infants had few abnormal neurologic findings as neonates, but hemiparesis became evident as gross motor development proceeded. Infants with strokes identified later in the first year of life usually presented with pathologic early hand preference without a history of an ictus. During subsequent development, the motor deficits in these children became more evident, producing an apparent progression of the neurologic abnormalities. Strokes identified in older children typically presented as sudden hemiparesis, often associated with seizures. The hemiparesis in these children was most severe at the onset, followed by some improvement in strength in all patients. Functional outcome was variable. At last follow-up, all children were ambulatory, some with clinically apparent hemiparesis. Eight of the 42 children (19%) developed recurrent seizures with an onset ranging from 4 months to more than 10 years (median: 26 months) after the stroke.
Similar articles
- Seizures associated with stroke in childhood.
Yang JS, Park YD, Hartlage PL. Yang JS, et al. Pediatr Neurol. 1995 Feb;12(2):136-8. doi: 10.1016/0887-8994(94)00152-r. Pediatr Neurol. 1995. PMID: 7779211 - Epilepsy in children with delayed presentation of perinatal stroke.
Fitzgerald KC, Williams LS, Garg BP, Golomb MR. Fitzgerald KC, et al. J Child Neurol. 2007 Nov;22(11):1274-80. doi: 10.1177/0883073807307106. J Child Neurol. 2007. PMID: 18006956 - Paradoxical ictal EEG lateralization in children with unilateral encephaloclastic lesions.
Garzon E, Gupta A, Bingaman W, Sakamoto AC, Lüders H. Garzon E, et al. Epileptic Disord. 2009 Sep;11(3):215-21. doi: 10.1684/epd.2009.0264. Epub 2009 Sep 9. Epileptic Disord. 2009. PMID: 19740718 - [Acute childhood hemiplegia ].
Velkey I. Velkey I. Orv Hetil. 1992 Nov 8;133(45):2893-6. Orv Hetil. 1992. PMID: 1437113 Review. Hungarian. - Cerebrovascular disorders in children.
Lynch JK. Lynch JK. Curr Neurol Neurosci Rep. 2004 Mar;4(2):129-38. doi: 10.1007/s11910-004-0027-3. Curr Neurol Neurosci Rep. 2004. PMID: 14984685 Review.
Cited by
- Hypothermia is correlated with seizure absence in perinatal stroke.
Harbert MJ, Tam EW, Glass HC, Bonifacio SL, Haeusslein LA, Barkovich AJ, Jeremy RJ, Rogers EE, Glidden DV, Ferriero DM. Harbert MJ, et al. J Child Neurol. 2011 Sep;26(9):1126-30. doi: 10.1177/0883073811408092. Epub 2011 Jun 23. J Child Neurol. 2011. PMID: 21700899 Free PMC article. - Role of brain inflammation in epileptogenesis.
Choi J, Koh S. Choi J, et al. Yonsei Med J. 2008 Feb 29;49(1):1-18. doi: 10.3349/ymj.2008.49.1.1. Yonsei Med J. 2008. PMID: 18306464 Free PMC article. Review. - Antithrombotic drug treatment of pediatric patients with ischemic stroke.
Nowak-Göttl U, Sträeter R, Sébire G, Kirkham F. Nowak-Göttl U, et al. Paediatr Drugs. 2003;5(3):167-75. doi: 10.2165/00128072-200305030-00003. Paediatr Drugs. 2003. PMID: 12608881 Review. - Ischemic stroke in infants and children: practical management in emergency.
Ciccone S, Cappella M, Borgna-Pignatti C. Ciccone S, et al. Stroke Res Treat. 2011;2011:736965. doi: 10.4061/2011/736965. Epub 2011 Jul 3. Stroke Res Treat. 2011. PMID: 21776365 Free PMC article. - A review of long-term EEG monitoring in critically ill children with hypoxic-ischemic encephalopathy, congenital heart disease, ECMO, and stroke.
Abend NS, Dlugos DJ, Clancy RR. Abend NS, et al. J Clin Neurophysiol. 2013 Apr;30(2):134-42. doi: 10.1097/WNP.0b013e3182872af9. J Clin Neurophysiol. 2013. PMID: 23545764 Free PMC article. Review.