The nuclear pore complex: oily spaghetti or gummy bear? - PubMed (original) (raw)
Review
. 2007 Aug 10;130(3):405-7.
doi: 10.1016/j.cell.2007.07.029.
Affiliations
- PMID: 17693250
- DOI: 10.1016/j.cell.2007.07.029
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Review
The nuclear pore complex: oily spaghetti or gummy bear?
Karsten Weis. Cell. 2007.
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Abstract
In this issue, Frey and Görlich (2007) provide new insight into the selective barrier that controls protein traffic through the nuclear pore complex. They show that a single protein domain of the nuclear pore protein Nsp1 can form a hydrogel that allows highly selective access of nuclear transport receptors and their cargos, but rejects other proteins of similar size.
Comment on
- A saturated FG-repeat hydrogel can reproduce the permeability properties of nuclear pore complexes.
Frey S, Görlich D. Frey S, et al. Cell. 2007 Aug 10;130(3):512-23. doi: 10.1016/j.cell.2007.06.024. Cell. 2007. PMID: 17693259
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