Femoral rather than carotid artery ultrasound imaging predicts extent and severity of coronary artery disease - PubMed (original) (raw)
. 2007 Jul;65(7):760-6; discussion 767-8.
Affiliations
- PMID: 17694457
Femoral rather than carotid artery ultrasound imaging predicts extent and severity of coronary artery disease
Cezary Sosnowski et al. Kardiol Pol. 2007 Jul.
Abstract
Background: Pathological, epidemiological and clinical studies indicate that there is coexistence between peripheral vascular disease and coronary artery disease (CAD). B-mode ultrasound of superficial arteries is a non-invasive, valid and reproducible method of directly visualising and assessing carotid and femoral intima-media thickness (IMT) and focal atherosclerosis.
Aim: To evaluate the prognostic importance of carotid and femoral vascular changes in predicting CAD severity.
Methods: 410 patients--300 (73.2%) males and 110 (26.8%) females--aged 29-75 years (mean age 55.9+/-9.5 years), referred for elective coronary arteriography, were studied. Clinical examination and laboratory tests were performed, and ultrasound assessments of IMT and atherosclerotic plaque thickness in the common carotid arteries and common femoral arteries were evaluated.
Results: Coronary angiography revealed CAD in 81% of patients (85% of males, 70% of females). Cox multiple hazards regression analyses showed a significant relationship between size of atherosclerotic plaques in peripheral arteries and CAD. Odds ratio of CAD associated with every 1-mm plaque thickening ranged from 1.7 to 3.0 (p <0.001) depending on examined artery. Using multiple stepwise regression analysis, the following parameters were found to be independent predictors of one-vessel CAD: myocardial infarction (MI) in anamnesis (OR=22.3; 95% CI 4.0-122.9), typical chest pain (OR=6.4; 95% CI 1.2-34.2), femoral IMT (OR=5.0; 95% CI 1.4-18.4), ex-smoking (OR=5.6; 95% CI 1.1-28.7), and pulse pressure (OR=1.8; 95% CI 1.0-3.2). Independent predictors of multi-vessel CAD were: MI (OR=3.7; 95% CI 1.8-7.5), typical angina (OR=3.3; 95% CI 1.7-6.5), age (OR=1.05; 95% CI 1.01-1.08), number of cigarettes smoked (OR=0.8; 95% CI 0.6-0.9), total cholesterol level (OR=1.1; 95% CI 1.0-1.2), and left femoral plaque thickness (OR=1.4; 95% CI 1.0-2.0).
Conclusion: Femoral IMT is an independent predictor of a single-vessel disease, whereas femoral atherosclerotic plaque presence indicates advanced CAD.
Similar articles
- [The role of ultrasonography of the peripheral arteries in diagnosing coronary artery disease].
Pasierski T, Sosnowski C, Szulczyk A, Leszczyński L, Rewicki M. Pasierski T, et al. Pol Arch Med Wewn. 2004 Jan;111(1):21-5. Pol Arch Med Wewn. 2004. PMID: 15088417 Polish. - Intima-media thickness is a useful marker of the extent of coronary artery disease in patients with impaired renal function.
Lisowska A, Musiał WJ, Lisowski P, Knapp M, Małyszko J, Dobrzycki S. Lisowska A, et al. Atherosclerosis. 2009 Feb;202(2):470-5. doi: 10.1016/j.atherosclerosis.2008.05.051. Epub 2008 Jun 5. Atherosclerosis. 2009. PMID: 18621374 Clinical Trial. - Is the lumen diameter of peripheral arteries a good marker of the extent of coronary atherosclerosis?
Mirek AM, Wolińska-Welcz A. Mirek AM, et al. Kardiol Pol. 2013;71(8):810-7. doi: 10.5603/KP.2013.0192. Kardiol Pol. 2013. PMID: 24049020 - [Intima media thickness of the carotid arteries: early pointer to arteriosclerosis and therapeutic endpoint].
Ludwig M, von Petzinger-Kruthoff A, von Buquoy M, Stumpe KO. Ludwig M, et al. Ultraschall Med. 2003 Jun;24(3):162-74. doi: 10.1055/s-2003-40058. Ultraschall Med. 2003. PMID: 12817310 Review. German. - Carotid ultrasound assessment of patients with coronary artery disease: a useful index for risk stratification.
Komorovsky R, Desideri A. Komorovsky R, et al. Vasc Health Risk Manag. 2005;1(2):131-6. doi: 10.2147/vhrm.1.2.131.64077. Vasc Health Risk Manag. 2005. PMID: 17315399 Free PMC article. Review.
Cited by
- Subclinical Atherosclerosis Progression in Low-Risk, Middle-Aged Adults: Carotid Leads Femoral in IMT Increase but Not in Plaque Formation.
Szabóová E, Lisovszki A, Rajnič A, Kolarčik P, Szabó P, Molnár T, Dekanová L. Szabóová E, et al. J Cardiovasc Dev Dis. 2024 Sep 2;11(9):271. doi: 10.3390/jcdd11090271. J Cardiovasc Dev Dis. 2024. PMID: 39330329 Free PMC article. - Impact of androgenic anabolic steroid use on cardiovascular and mental health in Danish recreational athletes: protocol for a nationwide cross-sectional cohort study as a part of the Fitness Doping in Denmark (FIDO-DK) study.
Buhl LF, Lehmann Christensen L, Diederichsen A, Lindholt JS, Kistorp CM, Glintborg D, Andersen M, Frystyk J. Buhl LF, et al. BMJ Open. 2024 May 7;14(5):e078558. doi: 10.1136/bmjopen-2023-078558. BMJ Open. 2024. PMID: 38719280 Free PMC article. - Peripheral Artery Disease Ultrasound Assessment in Predicting the Severity of Coronary Artery Disease.
Olinic M, Lazar FL, Onea HL, Homorodean C, Ober M, Tataru D, Spinu M, Achim A, Olinic DM. Olinic M, et al. Life (Basel). 2024 Mar 1;14(3):333. doi: 10.3390/life14030333. Life (Basel). 2024. PMID: 38541658 Free PMC article. Review. - Predictive Value of Noninvasive Peripheral Atherosclerosis Measurement for Coronary Artery Disease in Patients with Long T2DM Duration.
Chen W, Wang L, Hu B, Zheng Y, Zhang S, Zhou Z, Mai Y. Chen W, et al. Diabetes Metab Syndr Obes. 2023 Apr 18;16:1075-1083. doi: 10.2147/DMSO.S404937. eCollection 2023. Diabetes Metab Syndr Obes. 2023. PMID: 37095753 Free PMC article. - Vascular risk factors and staging of atherosclerosis in patients and controls: The Norwegian Stroke in the Young Study.
Nawaz B, Fromm A, Øygarden H, Eide GE, Saeed S, Meijer R, Bots ML, Sand KM, Thomassen L, Næss H, Waje-Andreassen U. Nawaz B, et al. Eur Stroke J. 2022 Sep;7(3):289-298. doi: 10.1177/23969873221098582. Epub 2022 May 10. Eur Stroke J. 2022. PMID: 36082261 Free PMC article.
MeSH terms
LinkOut - more resources
Medical
Miscellaneous