Targeted delivery of multifunctional magnetic nanoparticles - PubMed (original) (raw)
Review
Targeted delivery of multifunctional magnetic nanoparticles
Jason R McCarthy et al. Nanomedicine (Lond). 2007 Apr.
Abstract
Magnetic nanoparticles and their magnetofluorescent analogues have become important tools for in vivo imaging using magnetic resonance imaging and fluorescent optical methods. A number of monodisperse magnetic nanoparticle preparations have been developed over the last decade for angiogenesis imaging, cancer staging, tracking of immune cells (monocyte/macrophage, T cells) and for molecular and cellular targeting. Phage display and data mining have enabled the procurement of novel tissue- or receptor-specific peptides, while high-throughput screening of diversity-oriented synthesis libraries has identified small molecules that permit or prevent uptake by specific cell types. Next-generation magnetic nanoparticles are expected to be truly multifunctional, incorporating therapeutic functionalities and further enhancing an already diverse repertoire of capabilities.
Similar articles
- Recent advances on surface engineering of magnetic iron oxide nanoparticles and their biomedical applications.
Gupta AK, Naregalkar RR, Vaidya VD, Gupta M. Gupta AK, et al. Nanomedicine (Lond). 2007 Feb;2(1):23-39. doi: 10.2217/17435889.2.1.23. Nanomedicine (Lond). 2007. PMID: 17716188 Review. - Liposome-nanoparticle hybrids for multimodal diagnostic and therapeutic applications.
Al-Jamal WT, Kostarelos K. Al-Jamal WT, et al. Nanomedicine (Lond). 2007 Feb;2(1):85-98. doi: 10.2217/17435889.2.1.85. Nanomedicine (Lond). 2007. PMID: 17716195 Review. - Magnetic and fluorescent nanoparticles for multimodality imaging.
Mulder WJ, Griffioen AW, Strijkers GJ, Cormode DP, Nicolay K, Fayad ZA. Mulder WJ, et al. Nanomedicine (Lond). 2007 Jun;2(3):307-24. doi: 10.2217/17435889.2.3.307. Nanomedicine (Lond). 2007. PMID: 17716176 Review. - Targeted delivery of magnetic aerosol droplets to the lung.
Dames P, Gleich B, Flemmer A, Hajek K, Seidl N, Wiekhorst F, Eberbeck D, Bittmann I, Bergemann C, Weyh T, Trahms L, Rosenecker J, Rudolph C. Dames P, et al. Nat Nanotechnol. 2007 Aug;2(8):495-9. doi: 10.1038/nnano.2007.217. Epub 2007 Jul 22. Nat Nanotechnol. 2007. PMID: 18654347 - Promising approaches in using magnetic nanoparticles in oncology.
Mikhaylov G, Vasiljeva O. Mikhaylov G, et al. Biol Chem. 2011 Nov;392(11):955-60. doi: 10.1515/BC.2011.185. Biol Chem. 2011. PMID: 21848508 Review.
Cited by
- Limitations on the optical tunability of small diameter gold nanoshells.
Rasch MR, Sokolov KV, Korgel BA. Rasch MR, et al. Langmuir. 2009 Oct 6;25(19):11777-85. doi: 10.1021/la901249j. Langmuir. 2009. PMID: 19711913 Free PMC article. - Cubic magnetically guided nanoaggregates for inhalable drug delivery: in vitro magnetic aerosol deposition study.
Ragab DM, Rohani S. Ragab DM, et al. AAPS PharmSciTech. 2013 Sep;14(3):977-93. doi: 10.1208/s12249-013-9980-y. Epub 2013 Jun 14. AAPS PharmSciTech. 2013. PMID: 23765453 Free PMC article. - Leukocyte transepithelial migration in lung induced by DMSA functionalized magnetic nanoparticles.
Azevedo RB, Valois CR, Chaves SB, Silva JR, Garcia MP. Azevedo RB, et al. Cell Adh Migr. 2011 Jan-Feb;5(1):29-33. doi: 10.4161/cam.5.1.13558. Epub 2011 Jan 1. Cell Adh Migr. 2011. PMID: 20935452 Free PMC article. - Bioimaging Probes Based on Magneto-Fluorescent Nanoparticles.
Ganguly S, Margel S. Ganguly S, et al. Pharmaceutics. 2023 Feb 17;15(2):686. doi: 10.3390/pharmaceutics15020686. Pharmaceutics. 2023. PMID: 36840008 Free PMC article. Review. - Bio-distribution and toxicity assessment of intravenously injected anti-HER2 antibody conjugated CdSe/ZnS quantum dots in Wistar rats.
Tiwari DK, Jin T, Behari J. Tiwari DK, et al. Int J Nanomedicine. 2011;6:463-75. doi: 10.2147/IJN.S15124. Epub 2011 Feb 25. Int J Nanomedicine. 2011. PMID: 21499435 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources