Nitazoxanide: a review of its use in the treatment of gastrointestinal infections - PubMed (original) (raw)
Review
Nitazoxanide: a review of its use in the treatment of gastrointestinal infections
Vanessa R Anderson et al. Drugs. 2007.
Abstract
Nitazoxanide (Alinia, Daxon, Dexidex, Paramix, Kidonax, Colufase, Annita) has in vitro activity against a variety of microorganisms, including a broad range of protozoa and helminths. Nitazoxanide is effective in the treatment of protozoal and helminthic infections, including Cryptosporidium parvum or Giardia lamblia, in immunocompetent adults and children, and is generally well tolerated. Nitazoxanide is a first-line choice for the treatment of illness caused by C. parvum or G. lamblia infection in immunocompetent adults and children, and is an option to be considered in the treatment of illnesses caused by other protozoa and/or helminths.
Similar articles
- Epidemiology and control of intestinal parasites with nitazoxanide in children in Mexico.
Diaz E, Mondragon J, Ramirez E, Bernal R. Diaz E, et al. Am J Trop Med Hyg. 2003 Apr;68(4):384-5. Am J Trop Med Hyg. 2003. PMID: 12875284 - Nitazoxanide: clinical studies of a broad-spectrum anti-infective agent.
Aslam S, Musher DM. Aslam S, et al. Future Microbiol. 2007 Dec;2(6):583-90. doi: 10.2217/17460913.2.6.583. Future Microbiol. 2007. PMID: 18041899 - Nitazoxanide: a new broad spectrum antiparasitic agent.
White CA Jr. White CA Jr. Expert Rev Anti Infect Ther. 2004 Feb;2(1):43-9. doi: 10.1586/14787210.2.1.43. Expert Rev Anti Infect Ther. 2004. PMID: 15482170 Review. - Use of nitazoxanide as a new therapeutic option for persistent diarrhea: a pediatric perspective.
Cohen SA. Cohen SA. Curr Med Res Opin. 2005 Jul;21(7):999-1004. doi: 10.1185/030079905X50534. Curr Med Res Opin. 2005. PMID: 16004666 Review. - Nitazoxanide compared with quinfamide and mebendazole in the treatment of helminthic infections and intestinal protozoa in children.
Davila-Gutierrez CE, Vasquez C, Trujillo-Hernandez B, Huerta M. Davila-Gutierrez CE, et al. Am J Trop Med Hyg. 2002 Mar;66(3):251-4. doi: 10.4269/ajtmh.2002.66.251. Am J Trop Med Hyg. 2002. PMID: 12139216 Clinical Trial.
Cited by
- Biological activity of modified and exchanged 2-amino-5-nitrothiazole amide analogues of nitazoxanide.
Ballard TE, Wang X, Olekhnovich I, Koerner T, Seymour C, Hoffman PS, Macdonald TL. Ballard TE, et al. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3537-9. doi: 10.1016/j.bmcl.2010.04.126. Epub 2010 May 18. Bioorg Med Chem Lett. 2010. PMID: 20488706 Free PMC article. - Pathogen-driven gastrointestinal cancers: Time for a change in treatment paradigm?
Aituov B, Duisembekova A, Bulenova A, Alibek K. Aituov B, et al. Infect Agent Cancer. 2012 Aug 8;7(1):18. doi: 10.1186/1750-9378-7-18. Infect Agent Cancer. 2012. PMID: 22873119 Free PMC article. - Anthelmintics nitazoxanide protects against experimental hyperlipidemia and hepatic steatosis in hamsters and mice.
Li F, Jiang M, Ma M, Chen X, Zhang Y, Zhang Y, Yu Y, Cui Y, Chen J, Zhao H, Sun Z, Dong D. Li F, et al. Acta Pharm Sin B. 2022 Mar;12(3):1322-1338. doi: 10.1016/j.apsb.2021.09.009. Epub 2021 Sep 17. Acta Pharm Sin B. 2022. PMID: 35530137 Free PMC article. - The Tubulin Superfamily in Apicomplexan Parasites.
Morrissette N, Abbaali I, Ramakrishnan C, Hehl AB. Morrissette N, et al. Microorganisms. 2023 Mar 9;11(3):706. doi: 10.3390/microorganisms11030706. Microorganisms. 2023. PMID: 36985278 Free PMC article.
References
- J Antimicrob Chemother. 2000 Jul;46(1):57-60 - PubMed
- Curr Opin Infect Dis. 2001 Oct;14(5):587-91 - PubMed
- J Antimicrob Chemother. 2007 Aug;60(2):280-7 - PubMed
- Clin Infect Dis. 2000 Mar;30(3):419-24 - PubMed
- J Antimicrob Chemother. 2007 Apr;59(4):705-10 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical