Sensory transduction in the gliding bacterium Myxococcus xanthus - PubMed (original) (raw)

Review

Sensory transduction in the gliding bacterium Myxococcus xanthus

D R Zusman et al. Mol Microbiol. 1991 Oct.

Abstract

Sensory transduction in the gliding bacterium Myxococcus xanthus is mediated by the frz genes. These genes are homologous to the chemotaxis genes of enteric bacteria and control the rate of cell reversal during gliding. Sensory transduction is hypothesized to involve the recognition of substances present in the medium at the cell surface and the subsequent stimulation of a cytoplasmic methyl-accepting protein, FrzCD. Phosphorylation of FrzE is also involved in the sensory transduction pathway. Despite the similarities between the chemotaxis proteins of enteric bacteria and M. xanthus Frz proteins, fundamental differences exist between these different bacteria in terms of the ability of cells to recognize and respond to substances in their environment. The mechanism of directional switching and the nature of the gliding motor remain obscure. It is hoped that the study of the interaction of the Frz proteins will allow greater understanding of these problems.

PubMed Disclaimer

Similar articles

• Gliding motility in bacteria: insights from studies of Myxococcus xanthus.
  Spormann AM. Spormann AM. Microbiol Mol Biol Rev. 1999 Sep;63(3):621-41. doi: 10.1128/MMBR.63.3.621-641.1999. Microbiol Mol Biol Rev. 1999. PMID: 10477310 Free PMC article. Review.
• Methylation of FrzCD, a methyl-accepting taxis protein of Myxococcus xanthus, is correlated with factors affecting cell behavior.
  McBride MJ, Köhler T, Zusman DR. McBride MJ, et al. J Bacteriol. 1992 Jul;174(13):4246-57. doi: 10.1128/jb.174.13.4246-4257.1992. J Bacteriol. 1992. PMID: 1624419 Free PMC article.
• Analysis of the Frz signal transduction system of Myxococcus xanthus shows the importance of the conserved C-terminal region of the cytoplasmic chemoreceptor FrzCD in sensing signals.
  Bustamante VH, Martínez-Flores I, Vlamakis HC, Zusman DR. Bustamante VH, et al. Mol Microbiol. 2004 Sep;53(5):1501-13. doi: 10.1111/j.1365-2958.2004.04221.x. Mol Microbiol. 2004. PMID: 15387825
• Chemotaxis plays a role in the social behaviour of Myxococcus xanthus.
  Shi W, Köhler T, Zusman DR. Shi W, et al. Mol Microbiol. 1993 Aug;9(3):601-11. doi: 10.1111/j.1365-2958.1993.tb01720.x. Mol Microbiol. 1993. PMID: 8412706
• Regulation of directed motility in Myxococcus xanthus.
  Ward MJ, Zusman DR. Ward MJ, et al. Mol Microbiol. 1997 Jun;24(5):885-93. doi: 10.1046/j.1365-2958.1997.4261783.x. Mol Microbiol. 1997. PMID: 9219997 Review.

Cited by

• OsPAL2-1 Mediates Allelopathic Interactions Between Rice and Specific Microorganisms in the Rhizosphere Ecosystem.
  Li Y, Jian X, Li Y, Zeng X, Xu L, Khan MU, Lin W. Li Y, et al. Front Microbiol. 2020 Jul 23;11:1411. doi: 10.3389/fmicb.2020.01411. eCollection 2020. Front Microbiol. 2020. PMID: 32793125 Free PMC article.
• Gliding motility in bacteria: insights from studies of Myxococcus xanthus.
  Spormann AM. Spormann AM. Microbiol Mol Biol Rev. 1999 Sep;63(3):621-41. doi: 10.1128/MMBR.63.3.621-641.1999. Microbiol Mol Biol Rev. 1999. PMID: 10477310 Free PMC article. Review.
• The tgl gene: social motility and stimulation in Myxococcus xanthus.
  Rodriguez-Soto JP, Kaiser D. Rodriguez-Soto JP, et al. J Bacteriol. 1997 Jul;179(13):4361-71. doi: 10.1128/jb.179.13.4361-4371.1997. J Bacteriol. 1997. PMID: 9209055 Free PMC article.
• Further characterization and in situ localization of chain-like aggregates of the gliding bacteria Myxococcus fulvus and Myxococcus xanthus.
  Freese A, Reichenbach H, Lünsdorf H. Freese A, et al. J Bacteriol. 1997 Feb;179(4):1246-52. doi: 10.1128/jb.179.4.1246-1252.1997. J Bacteriol. 1997. PMID: 9023208 Free PMC article.
• Thermostable chemotaxis proteins from the hyperthermophilic bacterium Thermotoga maritima.
  Swanson RV, Sanna MG, Simon MI. Swanson RV, et al. J Bacteriol. 1996 Jan;178(2):484-9. doi: 10.1128/jb.178.2.484-489.1996. J Bacteriol. 1996. PMID: 8550470 Free PMC article.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Wiley