Network modeling links breast cancer susceptibility and centrosome dysfunction - PubMed (original) (raw)

• Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.
  Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubiński J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE; HEBON; EMBRACE; Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt Av; SWE-BRCA; Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldés T, Andrés R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigó R, Aiza G, Brunet J, Castellsagué J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, … See abstract for full author list ➔ Maxwell CA, et al. PLoS Biol. 2011 Nov;9(11):e1001199. doi: 10.1371/journal.pbio.1001199. Epub 2011 Nov 15. PLoS Biol. 2011. PMID: 22110403 Free PMC article.
• KIAA0101 interacts with BRCA1 and regulates centrosome number.
  Kais Z, Barsky SH, Mathsyaraja H, Zha A, Ransburgh DJ, He G, Pilarski RT, Shapiro CL, Huang K, Parvin JD. Kais Z, et al. Mol Cancer Res. 2011 Aug;9(8):1091-9. doi: 10.1158/1541-7786.MCR-10-0503. Epub 2011 Jun 14. Mol Cancer Res. 2011. PMID: 21673012 Free PMC article.
• Aurora-A kinase regulates breast cancer associated gene 1 inhibition of centrosome-dependent microtubule nucleation.
  Sankaran S, Crone DE, Palazzo RE, Parvin JD. Sankaran S, et al. Cancer Res. 2007 Dec 1;67(23):11186-94. doi: 10.1158/0008-5472.CAN-07-2578. Cancer Res. 2007. PMID: 18056443
• Dysregulation of the centrosome induced by BRCA1 deficiency contributes to tissue-specific carcinogenesis.
  Yoshino Y, Fang Z, Qi H, Kobayashi A, Chiba N. Yoshino Y, et al. Cancer Sci. 2021 May;112(5):1679-1687. doi: 10.1111/cas.14859. Epub 2021 Mar 16. Cancer Sci. 2021. PMID: 33606355 Free PMC article. Review.
• Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan Receptor.
  He Z, Mei L, Connell M, Maxwell CA. He Z, et al. Cells. 2020 Mar 28;9(4):819. doi: 10.3390/cells9040819. Cells. 2020. PMID: 32231069 Free PMC article. Review.