Ubiquitin signals in the NF-kappaB pathway - PubMed (original) (raw)

Review

. 2007 Nov;35(Pt 5):942-5.

doi: 10.1042/BST0350942.

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• PMID: 17956251
• DOI: 10.1042/BST0350942

Review

Ubiquitin signals in the NF-kappaB pathway

J Terzic et al. Biochem Soc Trans. 2007 Nov.

Abstract

The NF-kappaB (nuclear factor kappaB) transcription factors control cell survival, proliferation and innate and adaptive immune response. Post-translational modifications of key components of the NF-kappaB pathway provide the molecular basis for signal transmission from the cell membrane to the nucleus. Here, we describe the involvement of different types of ubiquitin modification in the regulation of the NF-kappaB signalling pathway.

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