FtsK and SpoIIIE: the tale of the conserved tails - PubMed (original) (raw)
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FtsK and SpoIIIE: the tale of the conserved tails
François-Xavier Barre. Mol Microbiol. 2007 Dec.
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Abstract
During Bacillus subtilis sporulation, the SpoIIIE DNA translocase moves a trapped chromosome across the sporulation septum into the forespore. The preferential assembly of SpoIIIE complexes in the mother cell provided the idea that SpoIIIE functioned as a DNA exporter, which ensured translocation orientation. In this issue of Molecular Microbiology, Becker and Pogliano reinvestigate the molecular mechanisms that orient the activity of SpoIIIE. Their findings indicate that SpoIIIE reads the polarity of DNA like its Escherichia coli homologue, FtsK.
Comment on
- Cell-specific SpoIIIE assembly and DNA translocation polarity are dictated by chromosome orientation.
Becker EC, Pogliano K. Becker EC, et al. Mol Microbiol. 2007 Dec;66(5):1066-79. doi: 10.1111/j.1365-2958.2007.05992.x. Mol Microbiol. 2007. PMID: 18001347 Free PMC article.
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