Imaging the neurochemistry of alcohol and substance abuse - PubMed (original) (raw)
Review
. 2007 Nov;17(4):539-55, x.
doi: 10.1016/j.nic.2007.07.004.
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- PMID: 17983969
- DOI: 10.1016/j.nic.2007.07.004
Review
Imaging the neurochemistry of alcohol and substance abuse
Diana Martinez et al. Neuroimaging Clin N Am. 2007 Nov.
Abstract
Animal models of abuse and dependence have long suggested that chronic drug and alcohol exposure is associated with marked changes in neurochemistry. The development of PET and SPECT imaging now allows investigation of the effects of addiction on the neurochemistry of the human brain. This article reviews the literature of radiochemical imaging in cocaine, alcohol, heroin, methamphetamine, MDMA, and ketamine abuse and dependence.
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