Imaging the genetics of executive function - PubMed (original) (raw)
Review
Imaging the genetics of executive function
Ciara M Greene et al. Biol Psychol. 2008 Sep.
Free article
Abstract
Recent advances in neuroimaging technologies have allowed ever more detailed studies of the human brain. The combination of neuroimaging techniques with genetics may provide a more sensitive measure of the influence of genetic variants on cognitive function than behavioural measures alone. Here we present a review of functional magnetic resonance imaging (fMRI) studies of genetic links to executive functions, focusing on sustained attention, working memory and response inhibition. In addition to studies in the normal population, we also address findings from three clinical populations: schizophrenia, ADHD and autism spectrum disorders. While the findings in the populations studied do not always converge, they all point to the usefulness of neuroimaging techniques such as fMRI as potential endophenotypes for parsing the genetic aetiology of executive function.
Similar articles
- [Structural and functional neuroanatomy of attention-deficit hyperactivity disorder (ADHD)].
Emond V, Joyal C, Poissant H. Emond V, et al. Encephale. 2009 Apr;35(2):107-14. doi: 10.1016/j.encep.2008.01.005. Epub 2008 Jul 7. Encephale. 2009. PMID: 19393378 Review. French. - Executive dysfunction in attention-deficit/hyperactivity disorder: cognitive and neuroimaging findings.
Roth RM, Saykin AJ. Roth RM, et al. Psychiatr Clin North Am. 2004 Mar;27(1):83-96, ix. doi: 10.1016/S0193-953X(03)00112-6. Psychiatr Clin North Am. 2004. PMID: 15062632 Review. - Intellectual deficits in children with ADHD beyond central executive and non-executive functions.
Tillman CM, Bohlin G, Sørensen L, Lundervold AJ. Tillman CM, et al. Arch Clin Neuropsychol. 2009 Dec;24(8):769-82. doi: 10.1093/arclin/acp075. Epub 2009 Oct 13. Arch Clin Neuropsychol. 2009. PMID: 19825866 - The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder.
Aron AR, Poldrack RA. Aron AR, et al. Biol Psychiatry. 2005 Jun 1;57(11):1285-92. doi: 10.1016/j.biopsych.2004.10.026. Epub 2004 Dec 23. Biol Psychiatry. 2005. PMID: 15950000 Review.
Cited by
- Effects of age and symptomatology on cortical thickness in autism spectrum disorders.
Doyle-Thomas KA, Duerden EG, Taylor MJ, Lerch JP, Soorya LV, Wang AT, Fan J, Hollander E, Anagnostou E. Doyle-Thomas KA, et al. Res Autism Spectr Disord. 2013 Jan;7(1):141-150. doi: 10.1016/j.rasd.2012.08.004. Res Autism Spectr Disord. 2013. PMID: 23678367 Free PMC article. - Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles.
Wang JY, Hessl D, Iwahashi C, Cheung K, Schneider A, Hagerman RJ, Hagerman PJ, Rivera SM. Wang JY, et al. Neuroimage. 2013 Jan 15;65:288-98. doi: 10.1016/j.neuroimage.2012.09.075. Epub 2012 Oct 12. Neuroimage. 2013. PMID: 23063447 Free PMC article. - Effects of AKAP5 Pro100Leu genotype on working memory for emotional stimuli.
Richter S, Gorny X, Machts J, Behnisch G, Wüstenberg T, Herbort MC, Münte TF, Seidenbecher CI, Schott BH. Richter S, et al. PLoS One. 2013;8(1):e55613. doi: 10.1371/journal.pone.0055613. Epub 2013 Jan 29. PLoS One. 2013. PMID: 23383244 Free PMC article. - Executive function in children with neurodevelopmental conditions: a systematic review and meta-analysis.
Sadozai AK, Sun C, Demetriou EA, Lampit A, Munro M, Perry N, Boulton KA, Guastella AJ. Sadozai AK, et al. Nat Hum Behav. 2024 Dec;8(12):2357-2366. doi: 10.1038/s41562-024-02000-9. Epub 2024 Oct 18. Nat Hum Behav. 2024. PMID: 39424962 Free PMC article. - Evaluation of planning dysfunction in attention deficit hyperactivity disorder and autistic spectrum disorders using the zoo map task.
Salcedo-Marin MD, Moreno-Granados JM, Ruiz-Veguilla M, Ferrin M. Salcedo-Marin MD, et al. Child Psychiatry Hum Dev. 2013 Feb;44(1):166-85. doi: 10.1007/s10578-012-0317-y. Child Psychiatry Hum Dev. 2013. PMID: 22729461
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical