New players in the regulation of ecdysone biosynthesis - PubMed (original) (raw)

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New players in the regulation of ecdysone biosynthesis

Xun Huang et al. J Genet Genomics. 2008 Jan.

Abstract

Insect ecdysone steroid hormone regulates major developmental transitions, such as molting and metamorphosis. The production of ecdysone correlates well with the timing of these transitions. Finding out how the ecdysone biosynthesis is regulated is crucial to fully understand these sophisticated developmental switches. Here we summarized recent findings in the regulation of ecdysone biosynthesis from the aspects of cell signaling, key biosynthetic enzymes and substrate cholesterol trafficking.

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