Targeting tumors with peptides from natural sources - PubMed (original) (raw)
Review
Targeting tumors with peptides from natural sources
Sujit K Bhutia et al. Trends Biotechnol. 2008 Apr.
Abstract
Peptide-based therapies offer the potential for non-genotoxic, genotype-specific alternatives, or adjuvants, to the current range of traditional cancer treatments. Such a patient-tailored cancer-cell-directed therapeutic approach should have fewer side effects and could well be more effective than the current drug- or combination-based regimens. Here, we review the potential of novel natural anticancer peptides such as necrotic peptides, apoptotic peptides, function-blocking peptides, antiangiogenic peptides and immunostimulatory peptides in the context of their ability to induce tumor regression. We focus on the therapeutic prospects of anticancer peptides and their possible application in tumor therapy.
Similar articles
- Anti-tumor chemotherapy utilizing peptide-based approaches--apoptotic pathways, kinases, and proteasome as targets.
Mendoza FJ, Espino PS, Cann KL, Bristow N, McCrea K, Los M. Mendoza FJ, et al. Arch Immunol Ther Exp (Warsz). 2005 Jan-Feb;53(1):47-60. Arch Immunol Ther Exp (Warsz). 2005. PMID: 15761376 Review. - Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides.
Raucher D, Moktan S, Massodi I, Bidwell GL 3rd. Raucher D, et al. Expert Opin Drug Deliv. 2009 Oct;6(10):1049-64. doi: 10.1517/17425240903158909. Expert Opin Drug Deliv. 2009. PMID: 19743895 Review. - Anti-angiogenic vaccines as a treatment modality for cancer.
Plum SM, Fogler WE. Plum SM, et al. Curr Opin Investig Drugs. 2004 Dec;5(12):1243-6. Curr Opin Investig Drugs. 2004. PMID: 15648944 Review. - Cancer treatment: what's ahead?
Parvez T. Parvez T. J Coll Physicians Surg Pak. 2005 Nov;15(11):738-45. J Coll Physicians Surg Pak. 2005. PMID: 16300718 Review. - Effects of cloned tumstatin-related and angiogenesis-inhibitory peptides on proliferation and apoptosis of endothelial cells.
Zhang GM, Zhang YM, Fu SB, Liu XH, Fu X, Yu Y, Zhang ZY. Zhang GM, et al. Chin Med J (Engl). 2008 Nov 20;121(22):2324-30. Chin Med J (Engl). 2008. PMID: 19080341
Cited by
- AC-1001 H3 CDR peptide induces apoptosis and signs of autophagy in vitro and exhibits antimetastatic activity in a syngeneic melanoma model.
Rabaça AN, Arruda DC, Figueiredo CR, Massaoka MH, Farias CF, Tada DB, Maia VC, Silva Junior PI, Girola N, Real F, Mortara RA, Polonelli L, Travassos LR. Rabaça AN, et al. FEBS Open Bio. 2016 Jul 15;6(9):885-901. doi: 10.1002/2211-5463.12080. eCollection 2016 Sep. FEBS Open Bio. 2016. PMID: 27642552 Free PMC article. - Lunasin: A promising polypeptide for the prevention and treatment of cancer.
Wan X, Liu H, Sun Y, Zhang J, Chen X, Chen N. Wan X, et al. Oncol Lett. 2017 Jun;13(6):3997-4001. doi: 10.3892/ol.2017.6017. Epub 2017 Apr 10. Oncol Lett. 2017. PMID: 28599405 Free PMC article. - Strategies to better treat glioblastoma: antiangiogenic agents and endothelial cell targeting agents.
Hasbum A, Quintanilla J, Jr JAA, Ding MH, Levy A, Chew SA. Hasbum A, et al. Future Med Chem. 2021 Feb;13(4):393-418. doi: 10.4155/fmc-2020-0289. Epub 2021 Jan 5. Future Med Chem. 2021. PMID: 33399488 Free PMC article. Review. - Anti-angiogenic peptides application in cancer therapy; a review.
Shoari A, Khodabakhsh F, Ahangari Cohan R, Salimian M, Karami E. Shoari A, et al. Res Pharm Sci. 2021 Oct 15;16(6):559-574. doi: 10.4103/1735-5362.327503. eCollection 2021 Dec. Res Pharm Sci. 2021. PMID: 34760005 Free PMC article. Review. - Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
Huang W, Seo J, Willingham SB, Czyzewski AM, Gonzalgo ML, Weissman IL, Barron AE. Huang W, et al. PLoS One. 2014 Feb 28;9(2):e90397. doi: 10.1371/journal.pone.0090397. eCollection 2014. PLoS One. 2014. PMID: 24587350 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources