Generation time and effective population size in Polar Eskimos - PubMed (original) (raw)
Comparative Study
Generation time and effective population size in Polar Eskimos
Shuichi Matsumura et al. Proc Biol Sci. 2008.
Abstract
North Greenland Polar Eskimos are the only hunter-gatherer population, to our knowledge, who can offer precise genealogical records spanning several generations. This is the first report from Eskimos on two key parameters in population genetics, namely, generation time (T) and effective population size (Ne). The average mother-daughter and father-son intervals were 27 and 32 years, respectively, roughly similar to the previously published generation times obtained from recent agricultural societies across the world. To gain an insight for the generation time in our distant ancestors, we calculated maternal generation time for two wild chimpanzee populations. We also provide the first comparison among three distinct approaches (genealogy, variance and life table methods) for calculating Ne, which resulted in slightly differing values for the Eskimos. The ratio of the effective to the census population size is estimated as 0.6-0.7 for autosomal and X-chromosomal DNA, 0.7-0.9 for mitochondrial DNA and 0.5 for Y-chromosomal DNA. A simulation of alleles along the genealogy suggested that Y-chromosomal DNA may drift a little faster than mitochondrial DNA in this population, in contrast to agricultural Icelanders. Our values will be useful not only in prehistoric population inference but also in understanding the shaping of our genome today.
Figures
Figure 1
(a) Mother–daughter intervals (_N_=379, mean=27.0, s.e.=0.38) and (b) father–son intervals (_N_=352, mean=32.1, s.e.=0.46).
Similar articles
- Mitochondrial genome diversity at the Bering Strait area highlights prehistoric human migrations from Siberia to northern North America.
Dryomov SV, Nazhmidenova AM, Shalaurova SA, Morozov IV, Tabarev AV, Starikovskaya EB, Sukernik RI. Dryomov SV, et al. Eur J Hum Genet. 2015 Oct;23(10):1399-404. doi: 10.1038/ejhg.2014.286. Epub 2015 Jan 7. Eur J Hum Genet. 2015. PMID: 25564040 Free PMC article. - The structure of the Polar Eskimo genealogy.
Edwards AW. Edwards AW. Hum Hered. 1992;42(4):242-52. doi: 10.1159/000154077. Hum Hered. 1992. PMID: 1512006 - PCR typing of DNA fragments of the two short tandem repeat (STR) systems upstream of the human myelin basic protein (MBP) gene in Danes and Greenland Eskimos.
Nellemann LJ, Frederiksen J, Morling N. Nellemann LJ, et al. Forensic Sci Int. 1996 Apr 2;78(2):139-56. doi: 10.1016/0379-0738(95)01882-4. Forensic Sci Int. 1996. PMID: 8621121 - [Genetic aspects of genealogy].
Tetushkin EIu. Tetushkin EIu. Genetika. 2011 Nov;47(11):1451-72. Genetika. 2011. PMID: 22332404 Review. Russian. - Otitis media in Greenland. Studies on historical, epidemiological, microbiological, and immunological aspects.
Homøe P. Homøe P. Int J Circumpolar Health. 2001;60 Suppl 2:1-54. Int J Circumpolar Health. 2001. PMID: 11725622 Review.
Cited by
- Human generation times across the past 250,000 years.
Wang RJ, Al-Saffar SI, Rogers J, Hahn MW. Wang RJ, et al. Sci Adv. 2023 Jan 6;9(1):eabm7047. doi: 10.1126/sciadv.abm7047. Epub 2023 Jan 6. Sci Adv. 2023. PMID: 36608127 Free PMC article. - GC-biased gene conversion in X-chromosome palindromes conserved in human, chimpanzee, and rhesus macaque.
Jackson EK, Bellott DW, Skaletsky H, Page DC. Jackson EK, et al. G3 (Bethesda). 2021 Oct 19;11(11):jkab224. doi: 10.1093/g3journal/jkab224. G3 (Bethesda). 2021. PMID: 34849781 Free PMC article. - Dating genomic variants and shared ancestry in population-scale sequencing data.
Albers PK, McVean G. Albers PK, et al. PLoS Biol. 2020 Jan 17;18(1):e3000586. doi: 10.1371/journal.pbio.3000586. eCollection 2020 Jan. PLoS Biol. 2020. PMID: 31951611 Free PMC article. - Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait.
Vicente M, Priehodová E, Diallo I, Podgorná E, Poloni ES, Černý V, Schlebusch CM. Vicente M, et al. BMC Genomics. 2019 Dec 2;20(1):915. doi: 10.1186/s12864-019-6296-7. BMC Genomics. 2019. PMID: 31791255 Free PMC article. - Island Rule, quantitative genetics and brain-body size evolution in Homo floresiensis.
Diniz-Filho JAF, Raia P. Diniz-Filho JAF, et al. Proc Biol Sci. 2017 Jun 28;284(1857):20171065. doi: 10.1098/rspb.2017.1065. Proc Biol Sci. 2017. PMID: 28637851 Free PMC article.
References
- Beaumont M.A. Recent developments in genetic data analysis: what can they tell us about human demographic history? Heredity. 2004;92:365–379. doi:10.1038/sj.hdy.6800447 - DOI - PubMed
- Boesch C, Boesch-Achermann H. Oxford University Press; Oxford, UK: 2000. The chimpanzees of the Taï forest.
- Crow J.F, Kimura M. Harper & Row; New York, NY: 1970. An introduction to population genetic theory.
- Crow J.F, Morton N.E. Measurement of gene frequency drift in small populations. Evolution. 1955;9:202–214. doi:10.2307/2405589 - DOI
- Edwards, A. W. F. 1968 Simulation studies of genealogies. (Abstract). Heredity23, 628.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources