Aging of the immune system as a prognostic factor for human longevity - PubMed (original) (raw)
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Aging of the immune system as a prognostic factor for human longevity
Anis Larbi et al. Physiology (Bethesda). 2008 Apr.
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Abstract
Accumulating data are documenting an inverse relationship between immune status, response to vaccination, health, and longevity, suggesting that the immune system becomes less effective with advancing age and that this is clinically relevant. The mechanisms and consequences of age-associated immune alterations, designated immunosenescence, are briefly reviewed here.
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